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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LMAN1L All Species: 8.18
Human Site: S499 Identified Species: 20
UniProt: Q9HAT1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAT1 NP_068591.2 526 57129 S499 Q E C L S T G S L P L G P A P
Chimpanzee Pan troglodytes XP_001143039 510 57514 P471 P K C P E L P P F P S C L S T
Rhesus Macaque Macaca mulatta XP_001097975 478 51638 S451 Q E C L S T G S L P L G P A P
Dog Lupus familis XP_544775 536 58667 S507 Q D C L S T G S H Q C P A P H
Cat Felis silvestris
Mouse Mus musculus Q8VCD3 374 41406 Q348 Q Q L G S T V Q V R P E G G W
Rat Rattus norvegicus Q62902 517 57939 H487 P S C L S T V H F V I F I V V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520748 360 40039 A334 S E K M T Q T A A Q W K H Q L
Chicken Gallus gallus NP_001026570 503 56501 S470 P P F P S C L S T V H F F I F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_688661 503 56848 S470 P P L P T C L S T T H F L I F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780803 509 57721 P467 T Q Q A I C P P A P E M P S C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 32.1 69.9 68.2 N.A. 50.5 32.1 N.A. 39.7 30.2 N.A. 31.3 N.A. N.A. N.A. N.A. 27
Protein Similarity: 100 48.2 75.6 75.3 N.A. 56 49.6 N.A. 49.8 47.5 N.A. 50.5 N.A. N.A. N.A. N.A. 43.9
P-Site Identity: 100 13.3 100 46.6 N.A. 20 26.6 N.A. 6.6 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 26.6 100 53.3 N.A. 33.3 33.3 N.A. 26.6 13.3 N.A. 13.3 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 10 20 0 0 0 10 20 0 % A
% Cys: 0 0 50 0 0 30 0 0 0 0 10 10 0 0 10 % C
% Asp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 30 0 0 10 0 0 0 0 0 10 10 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 20 0 0 30 10 0 20 % F
% Gly: 0 0 0 10 0 0 30 0 0 0 0 20 10 10 0 % G
% His: 0 0 0 0 0 0 0 10 10 0 20 0 10 0 10 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 10 0 10 20 0 % I
% Lys: 0 10 10 0 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 0 20 40 0 10 20 0 20 0 20 0 20 0 10 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 40 20 0 30 0 0 20 20 0 40 10 10 30 10 20 % P
% Gln: 40 20 10 0 0 10 0 10 0 20 0 0 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 10 10 0 0 60 0 0 50 0 0 10 0 0 20 0 % S
% Thr: 10 0 0 0 20 50 10 0 20 10 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 20 0 10 20 0 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 10 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _