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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SIAE All Species: 13.03
Human Site: S158 Identified Species: 35.83
UniProt: Q9HAT2 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAT2 NP_733746.1 523 58315 S158 S V R I L S V S P I Q A E Q E
Chimpanzee Pan troglodytes XP_508836 523 58312 S158 S V R I L S V S P I Q A E Q E
Rhesus Macaque Macaca mulatta XP_001109153 523 58446 S158 S V R I L S V S P I Q A E Q E
Dog Lupus familis XP_546429 510 57123 R154 T A A Y Q S V R I F S V S L I
Cat Felis silvestris
Mouse Mus musculus P70665 541 60757 S158 S V R I F S V S L I Q S E E E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516520 169 18307
Chicken Gallus gallus
Frog Xenopus laevis NP_001088190 516 58496 A156 N I R L F T A A L E V S L M E
Zebra Danio Brachydanio rerio NP_001037796 509 56606 A152 D V R I F Q A A L E Q S K K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789419 519 57698 P145 Q P W S L P N P G G Q T D K F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 97.1 80.3 N.A. 76.5 N.A. N.A. 23.1 N.A. 53.1 49.1 N.A. N.A. N.A. N.A. 41.1
Protein Similarity: 100 99.8 98.4 87.5 N.A. 84.6 N.A. N.A. 27.1 N.A. 68.8 64.6 N.A. N.A. N.A. N.A. 54.6
P-Site Identity: 100 100 100 13.3 N.A. 73.3 N.A. N.A. 0 N.A. 13.3 33.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 20 N.A. 86.6 N.A. N.A. 0 N.A. 53.3 60 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 12 0 0 0 23 23 0 0 0 34 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 23 0 0 45 12 67 % E
% Phe: 0 0 0 0 34 0 0 0 0 12 0 0 0 0 12 % F
% Gly: 0 0 0 0 0 0 0 0 12 12 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 56 0 0 0 0 12 45 0 0 0 0 12 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 12 23 0 % K
% Leu: 0 0 0 12 45 0 0 0 34 0 0 0 12 12 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % M
% Asn: 12 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % N
% Pro: 0 12 0 0 0 12 0 12 34 0 0 0 0 0 0 % P
% Gln: 12 0 0 0 12 12 0 0 0 0 67 0 0 34 0 % Q
% Arg: 0 0 67 0 0 0 0 12 0 0 0 0 0 0 0 % R
% Ser: 45 0 0 12 0 56 0 45 0 0 12 34 12 0 0 % S
% Thr: 12 0 0 0 0 12 0 0 0 0 0 12 0 0 0 % T
% Val: 0 56 0 0 0 0 56 0 0 0 12 12 0 0 0 % V
% Trp: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _