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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIAE
All Species:
18.48
Human Site:
S74
Identified Species:
50.83
UniProt:
Q9HAT2
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAT2
NP_733746.1
523
58315
S74
T
I
M
K
K
V
T
S
V
K
A
H
S
D
T
Chimpanzee
Pan troglodytes
XP_508836
523
58312
S74
T
I
M
K
K
V
T
S
V
K
A
H
S
D
T
Rhesus Macaque
Macaca mulatta
XP_001109153
523
58446
S74
T
I
M
K
K
V
T
S
V
K
A
H
F
D
T
Dog
Lupus familis
XP_546429
510
57123
S75
T
I
M
E
K
V
T
S
V
K
A
H
S
N
S
Cat
Felis silvestris
Mouse
Mus musculus
P70665
541
60757
S74
T
I
M
K
K
V
T
S
V
K
E
P
S
N
T
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516520
169
18307
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088190
516
58496
A72
T
I
L
K
K
S
V
A
I
N
D
D
A
G
V
Zebra Danio
Brachydanio rerio
NP_001037796
509
56606
P72
L
E
Q
T
Y
I
A
P
V
I
N
G
I
W
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789419
519
57698
S65
P
F
T
I
K
V
T
S
N
N
Q
G
V
Q
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
97.1
80.3
N.A.
76.5
N.A.
N.A.
23.1
N.A.
53.1
49.1
N.A.
N.A.
N.A.
N.A.
41.1
Protein Similarity:
100
99.8
98.4
87.5
N.A.
84.6
N.A.
N.A.
27.1
N.A.
68.8
64.6
N.A.
N.A.
N.A.
N.A.
54.6
P-Site Identity:
100
100
93.3
80
N.A.
80
N.A.
N.A.
0
N.A.
26.6
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
93.3
100
N.A.
86.6
N.A.
N.A.
0
N.A.
53.3
13.3
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
12
0
0
45
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
12
12
0
34
0
% D
% Glu:
0
12
0
12
0
0
0
0
0
0
12
0
0
0
12
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
23
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
45
0
0
0
% H
% Ile:
0
67
0
12
0
12
0
0
12
12
0
0
12
0
0
% I
% Lys:
0
0
0
56
78
0
0
0
0
56
0
0
0
0
0
% K
% Leu:
12
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
56
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
12
23
12
0
0
23
0
% N
% Pro:
12
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
12
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
0
0
0
0
0
12
0
67
0
0
0
0
45
0
12
% S
% Thr:
67
0
12
12
0
0
67
0
0
0
0
0
0
0
45
% T
% Val:
0
0
0
0
0
67
12
0
67
0
0
0
12
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _