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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHA5
All Species:
9.09
Human Site:
S146
Identified Species:
25
UniProt:
Q9HAU0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAU0
NP_001137293.1
1116
127464
S146
M
S
P
V
G
R
T
S
R
A
S
K
K
V
H
Chimpanzee
Pan troglodytes
XP_520779
1235
141111
R143
S
P
V
G
R
T
S
R
A
S
K
K
V
H
N
Rhesus Macaque
Macaca mulatta
XP_001093182
965
110499
G50
T
G
E
A
V
V
T
G
H
R
R
Q
S
T
D
Dog
Lupus familis
XP_534874
1284
146925
S147
M
S
P
V
G
R
T
S
R
A
S
K
K
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q3UIL6
1118
126724
S143
G
P
K
I
V
K
S
S
S
K
V
H
S
F
G
Rat
Rattus norvegicus
P60669
779
85624
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513654
574
63754
Chicken
Gallus gallus
XP_416414
1075
122045
F143
K
L
W
K
K
R
W
F
V
L
S
D
L
C
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695683
1238
141136
S146
S
S
P
T
T
R
P
S
R
S
S
K
K
V
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.6
63.7
81.3
N.A.
31.2
24.2
N.A.
21.5
74.4
N.A.
52.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
88.4
72.4
83.8
N.A.
49.5
36.7
N.A.
32.1
83
N.A.
65.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
100
N.A.
6.6
0
N.A.
0
13.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
13.3
100
N.A.
26.6
0
N.A.
0
13.3
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
12
23
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% D
% Glu:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
0
% F
% Gly:
12
12
0
12
23
0
0
12
0
0
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
12
0
12
34
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
12
12
12
12
0
0
0
12
12
45
34
0
0
% K
% Leu:
0
12
0
0
0
0
0
0
0
12
0
0
12
0
12
% L
% Met:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
23
34
0
0
0
12
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Q
% Arg:
0
0
0
0
12
45
0
12
34
12
12
0
0
0
0
% R
% Ser:
23
34
0
0
0
0
23
45
12
23
45
0
23
0
0
% S
% Thr:
12
0
0
12
12
12
34
0
0
0
0
0
0
12
0
% T
% Val:
0
0
12
23
23
12
0
0
12
0
12
0
12
34
0
% V
% Trp:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _