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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMURF2
All Species:
34.55
Human Site:
S213
Identified Species:
63.33
UniProt:
Q9HAU4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAU4
NP_073576.1
748
86196
S213
V
D
E
N
T
P
I
S
G
T
N
G
A
T
C
Chimpanzee
Pan troglodytes
XP_511577
1009
112809
S474
V
D
E
N
T
P
I
S
G
T
N
G
A
T
C
Rhesus Macaque
Macaca mulatta
XP_001109913
898
102762
S363
V
D
E
N
T
P
I
S
G
T
N
G
A
T
C
Dog
Lupus familis
XP_537589
738
85186
S203
V
D
E
N
T
P
I
S
G
T
N
G
A
T
C
Cat
Felis silvestris
Mouse
Mus musculus
A2A5Z6
748
86156
T213
V
D
E
N
T
P
I
T
G
T
N
G
A
T
C
Rat
Rattus norvegicus
Q62940
887
102376
R302
A
H
G
A
F
T
T
R
R
Q
I
S
E
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510726
748
86093
T213
V
D
E
N
T
P
I
T
G
T
N
G
A
T
S
Chicken
Gallus gallus
XP_425380
753
86808
T213
V
D
E
N
T
P
I
T
G
T
N
G
A
T
C
Frog
Xenopus laevis
Q2TAS2
751
86306
T213
V
D
E
N
T
P
I
T
G
T
N
G
A
S
C
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
M213
V
D
E
N
T
P
I
M
T
P
N
G
A
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V853
1061
115657
S223
H
N
T
H
N
G
N
S
G
D
R
Q
A
P
A
Honey Bee
Apis mellifera
XP_396318
779
88933
V239
N
G
N
Q
N
G
N
V
R
S
D
R
S
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
S216
R
S
T
N
S
T
S
S
A
T
R
Q
Y
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
82.7
97.1
N.A.
99.1
34
N.A.
98.6
97.8
95
90.8
N.A.
46
68
N.A.
N.A.
Protein Similarity:
100
74.1
83.1
97.5
N.A.
99.5
50.8
N.A.
99.1
98.4
97.1
94.1
N.A.
57.1
77.9
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
86.6
93.3
86.6
66.6
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
93.3
100
100
66.6
N.A.
33.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
8
0
0
0
77
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
54
% C
% Asp:
0
70
0
0
0
0
0
0
0
8
8
0
0
8
0
% D
% Glu:
0
0
70
0
0
0
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
16
0
0
70
0
0
70
0
0
8
% G
% His:
8
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
70
0
0
0
8
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
77
16
0
16
0
0
0
70
0
0
0
8
% N
% Pro:
0
0
0
0
0
70
0
0
0
8
0
0
0
8
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
8
0
16
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
8
16
0
16
8
0
0
0
% R
% Ser:
0
8
0
0
8
0
8
47
0
8
0
8
8
16
16
% S
% Thr:
0
0
16
0
70
16
8
31
8
70
0
0
0
54
0
% T
% Val:
70
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _