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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SMURF2 All Species: 13.33
Human Site: S354 Identified Species: 24.44
UniProt: Q9HAU4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAU4 NP_073576.1 748 86196 S354 Q Q Q Q Q V V S L C P D D T E
Chimpanzee Pan troglodytes XP_511577 1009 112809 S615 Q Q Q Q Q V V S L C P D D T E
Rhesus Macaque Macaca mulatta XP_001109913 898 102762 S504 Q Q Q Q Q V V S L C P D D T E
Dog Lupus familis XP_537589 738 85186 P344 Q Q Q Q Q V V P F C P D D A E
Cat Felis silvestris
Mouse Mus musculus A2A5Z6 748 86156 P354 Q Q Q Q Q V V P L C P D D T E
Rat Rattus norvegicus Q62940 887 102376 P490 K K T Q W E D P R M Q N V A I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510726 748 86093 S354 Q Q Q Q Q L V S L C P D E A E
Chicken Gallus gallus XP_425380 753 86808 C359 Q Q Q V V S L C Q L P D E A E
Frog Xenopus laevis Q2TAS2 751 86306 C357 P P Q V V S L C Q L P D E V E
Zebra Danio Brachydanio rerio A9JRZ0 765 87445 G371 A Q S V V S P G N L P E D P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V853 1061 115657 L663 P H R I V P D L P Q G L L E G
Honey Bee Apis mellifera XP_396318 779 88933 E384 Q N A Q T V S E L P K E L M D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P39940 809 91798 D417 T K T T T W D D P R L P S S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.1 82.7 97.1 N.A. 99.1 34 N.A. 98.6 97.8 95 90.8 N.A. 46 68 N.A. N.A.
Protein Similarity: 100 74.1 83.1 97.5 N.A. 99.5 50.8 N.A. 99.1 98.4 97.1 94.1 N.A. 57.1 77.9 N.A. N.A.
P-Site Identity: 100 100 100 80 N.A. 93.3 6.6 N.A. 80 40 26.6 26.6 N.A. 0 26.6 N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 93.3 26.6 N.A. 93.3 53.3 40 33.3 N.A. 6.6 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 37.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 54.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 0 0 0 0 0 0 0 0 0 0 31 0 % A
% Cys: 0 0 0 0 0 0 0 16 0 47 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 24 8 0 0 0 62 47 0 8 % D
% Glu: 0 0 0 0 0 8 0 8 0 0 0 16 24 8 70 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 8 0 0 8 0 0 0 8 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % I
% Lys: 8 16 0 0 0 0 0 0 0 0 8 0 0 0 0 % K
% Leu: 0 0 0 0 0 8 16 8 47 24 8 8 16 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % M
% Asn: 0 8 0 0 0 0 0 0 8 0 0 8 0 0 0 % N
% Pro: 16 8 0 0 0 8 8 24 16 8 70 8 0 8 0 % P
% Gln: 62 62 62 62 47 0 0 0 16 8 8 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 8 8 0 0 0 0 0 % R
% Ser: 0 0 8 0 0 24 8 31 0 0 0 0 8 8 0 % S
% Thr: 8 0 16 8 16 0 0 0 0 0 0 0 0 31 0 % T
% Val: 0 0 0 24 31 47 47 0 0 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 8 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _