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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMURF2
All Species:
51.82
Human Site:
S532
Identified Species:
95
UniProt:
Q9HAU4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAU4
NP_073576.1
748
86196
S532
V
D
P
D
L
H
N
S
L
V
W
I
L
E
N
Chimpanzee
Pan troglodytes
XP_511577
1009
112809
S793
V
D
P
D
L
H
N
S
L
V
W
I
L
E
N
Rhesus Macaque
Macaca mulatta
XP_001109913
898
102762
S682
V
D
P
D
L
H
N
S
L
V
W
I
L
E
N
Dog
Lupus familis
XP_537589
738
85186
S522
V
D
P
D
L
H
N
S
L
V
W
I
L
E
N
Cat
Felis silvestris
Mouse
Mus musculus
A2A5Z6
748
86156
S532
V
D
P
D
L
H
N
S
L
V
W
I
L
E
N
Rat
Rattus norvegicus
Q62940
887
102376
S671
V
D
S
E
Y
Y
S
S
L
R
W
I
L
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510726
748
86093
S532
V
D
P
D
L
H
N
S
L
V
W
I
L
E
N
Chicken
Gallus gallus
XP_425380
753
86808
S537
V
D
P
D
L
H
N
S
L
V
W
I
L
E
N
Frog
Xenopus laevis
Q2TAS2
751
86306
S535
V
D
P
D
L
H
N
S
L
V
W
I
L
E
N
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
S549
V
D
P
D
L
H
N
S
L
V
W
I
L
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V853
1061
115657
S841
V
D
P
D
L
H
R
S
L
T
W
M
L
E
S
Honey Bee
Apis mellifera
XP_396318
779
88933
S562
V
D
P
E
L
H
R
S
L
T
W
M
L
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
S594
V
D
A
E
V
Y
N
S
L
N
W
M
L
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
82.7
97.1
N.A.
99.1
34
N.A.
98.6
97.8
95
90.8
N.A.
46
68
N.A.
N.A.
Protein Similarity:
100
74.1
83.1
97.5
N.A.
99.5
50.8
N.A.
99.1
98.4
97.1
94.1
N.A.
57.1
77.9
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
60
N.A.
100
100
100
93.3
N.A.
73.3
73.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
100
100
100
100
N.A.
86.6
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
100
0
77
0
0
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
0
24
0
0
0
0
0
0
0
0
0
93
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
85
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
77
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
85
0
0
0
100
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
24
0
0
0
% M
% Asn:
0
0
0
0
0
0
77
0
0
8
0
0
0
0
93
% N
% Pro:
0
0
85
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
16
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
8
100
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% T
% Val:
100
0
0
0
8
0
0
0
0
70
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% W
% Tyr:
0
0
0
0
8
16
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _