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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMURF2
All Species:
27.27
Human Site:
T616
Identified Species:
50
UniProt:
Q9HAU4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAU4
NP_073576.1
748
86196
T616
I
P
Q
H
L
L
K
T
F
D
E
K
E
L
E
Chimpanzee
Pan troglodytes
XP_511577
1009
112809
T877
I
P
Q
H
L
L
K
T
F
D
E
K
E
L
E
Rhesus Macaque
Macaca mulatta
XP_001109913
898
102762
T766
I
P
Q
H
L
L
K
T
F
D
E
K
E
L
E
Dog
Lupus familis
XP_537589
738
85186
T606
I
P
Q
H
L
L
K
T
F
D
E
K
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
A2A5Z6
748
86156
T616
I
P
Q
H
L
L
K
T
F
D
E
K
E
L
E
Rat
Rattus norvegicus
Q62940
887
102376
I754
I
P
Q
D
L
I
K
I
F
D
E
N
E
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510726
748
86093
T616
I
P
Q
H
L
L
K
T
F
D
E
K
E
L
E
Chicken
Gallus gallus
XP_425380
753
86808
T621
I
P
Q
H
L
L
K
T
F
D
E
K
E
L
E
Frog
Xenopus laevis
Q2TAS2
751
86306
A619
I
P
Q
H
L
L
K
A
F
D
E
K
E
L
E
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
A633
I
P
Q
H
L
L
K
A
F
D
E
K
E
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V853
1061
115657
P925
I
P
S
H
L
L
R
P
F
D
E
R
E
L
E
Honey Bee
Apis mellifera
XP_396318
779
88933
P646
I
P
P
Q
L
L
R
P
F
D
E
R
E
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
V678
I
P
E
D
L
V
T
V
F
D
E
R
E
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
82.7
97.1
N.A.
99.1
34
N.A.
98.6
97.8
95
90.8
N.A.
46
68
N.A.
N.A.
Protein Similarity:
100
74.1
83.1
97.5
N.A.
99.5
50.8
N.A.
99.1
98.4
97.1
94.1
N.A.
57.1
77.9
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
73.3
N.A.
100
100
93.3
93.3
N.A.
73.3
66.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
100
100
93.3
93.3
N.A.
86.6
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
0
0
0
0
0
100
0
0
0
0
0
% D
% Glu:
0
0
8
0
0
0
0
0
0
0
100
0
100
0
100
% E
% Phe:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
77
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
100
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
77
0
0
0
0
70
0
0
0
% K
% Leu:
0
0
0
0
100
85
0
0
0
0
0
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
100
8
0
0
0
0
16
0
0
0
0
0
0
0
% P
% Gln:
0
0
77
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
16
0
0
0
0
24
0
0
0
% R
% Ser:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
54
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _