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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMURF2
All Species:
45.45
Human Site:
Y581
Identified Species:
83.33
UniProt:
Q9HAU4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAU4
NP_073576.1
748
86196
Y581
N
E
E
N
K
K
E
Y
V
R
L
Y
V
N
W
Chimpanzee
Pan troglodytes
XP_511577
1009
112809
Y842
N
E
E
N
K
K
E
Y
V
R
L
Y
V
N
W
Rhesus Macaque
Macaca mulatta
XP_001109913
898
102762
Y731
N
E
E
N
K
K
E
Y
V
R
L
Y
V
N
W
Dog
Lupus familis
XP_537589
738
85186
Y571
T
E
E
N
K
K
E
Y
V
R
L
Y
V
N
W
Cat
Felis silvestris
Mouse
Mus musculus
A2A5Z6
748
86156
Y581
T
E
E
N
K
K
E
Y
V
R
L
Y
V
N
W
Rat
Rattus norvegicus
Q62940
887
102376
I720
N
K
N
K
K
E
Y
I
Y
L
V
I
Q
W
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510726
748
86093
Y581
T
E
E
N
K
K
E
Y
V
R
L
Y
V
N
W
Chicken
Gallus gallus
XP_425380
753
86808
Y586
T
E
E
N
K
K
E
Y
V
R
L
Y
V
N
W
Frog
Xenopus laevis
Q2TAS2
751
86306
Y584
T
E
D
T
K
K
E
Y
V
R
L
Y
V
N
W
Zebra Danio
Brachydanio rerio
A9JRZ0
765
87445
Y598
T
Q
D
T
K
K
E
Y
V
R
L
Y
V
N
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V853
1061
115657
Y890
T
E
E
N
K
R
E
Y
V
K
L
Y
V
N
Y
Honey Bee
Apis mellifera
XP_396318
779
88933
Y611
T
E
E
N
K
K
E
Y
V
R
L
Y
V
N
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39940
809
91798
Y643
T
D
G
N
K
K
E
Y
V
E
L
Y
T
Q
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
82.7
97.1
N.A.
99.1
34
N.A.
98.6
97.8
95
90.8
N.A.
46
68
N.A.
N.A.
Protein Similarity:
100
74.1
83.1
97.5
N.A.
99.5
50.8
N.A.
99.1
98.4
97.1
94.1
N.A.
57.1
77.9
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
93.3
93.3
80
73.3
N.A.
73.3
86.6
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
93.3
93.3
86.6
86.6
N.A.
93.3
93.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
54.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
16
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
77
70
0
0
8
93
0
0
8
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% I
% Lys:
0
8
0
8
100
85
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
8
93
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
31
0
8
77
0
0
0
0
0
0
0
0
0
85
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
8
0
0
0
77
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
70
0
0
16
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
0
0
0
0
0
0
0
0
93
0
8
0
85
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
77
% W
% Tyr:
0
0
0
0
0
0
8
93
8
0
0
93
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _