KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UPF2
All Species:
24.24
Human Site:
S1165
Identified Species:
44.44
UniProt:
Q9HAU5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAU5
NP_056357.1
1272
147810
S1165
G
G
E
G
E
A
E
S
A
D
T
M
P
F
V
Chimpanzee
Pan troglodytes
XP_507656
1448
165981
S1341
G
G
E
G
E
A
E
S
A
D
T
M
P
F
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_857902
1271
147822
S1164
G
G
E
G
E
T
E
S
A
D
T
M
P
F
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074601
1269
147534
S1162
G
G
E
G
E
T
E
S
A
D
T
M
P
F
V
Rat
Rattus norvegicus
NP_001101891
1268
147324
S1161
G
G
E
G
E
T
E
S
A
D
T
M
P
F
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417288
1272
147721
S1165
S
G
E
G
E
S
E
S
G
D
T
M
P
F
V
Frog
Xenopus laevis
NP_001089661
1264
146847
S1157
I
A
E
V
D
T
E
S
G
D
T
M
P
F
V
Zebra Danio
Brachydanio rerio
XP_697460
594
68181
E498
A
S
P
L
D
P
P
E
H
L
F
R
I
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572434
1241
140038
G1137
A
G
A
A
G
A
S
G
A
T
S
V
P
F
V
Honey Bee
Apis mellifera
XP_396597
1132
130343
N1028
L
Q
E
R
P
S
D
N
S
T
V
D
F
V
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002315268
1194
135972
G1079
D
E
D
E
G
A
G
G
N
K
D
V
Q
V
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181459
1181
133943
E1069
V
L
D
E
E
N
G
E
Q
R
E
V
Q
V
K
Baker's Yeast
Sacchar. cerevisiae
P38798
1089
126729
K993
I
D
A
R
K
S
E
K
V
V
A
S
K
I
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
N.A.
97.7
N.A.
96.9
97
N.A.
N.A.
93.2
86.4
40
N.A.
36.3
45.5
N.A.
N.A.
Protein Similarity:
100
87.7
N.A.
99
N.A.
98.7
98.6
N.A.
N.A.
97.4
93.2
44.2
N.A.
56
62.8
N.A.
N.A.
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
60
0
N.A.
40
6.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
86.6
66.6
13.3
N.A.
53.3
40
N.A.
N.A.
Percent
Protein Identity:
37.1
N.A.
N.A.
34.4
21.3
N.A.
Protein Similarity:
54.2
N.A.
N.A.
53
40.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
16
8
0
31
0
0
47
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
16
0
16
0
8
0
0
54
8
8
0
0
0
% D
% Glu:
0
8
62
16
54
0
62
16
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
8
62
0
% F
% Gly:
39
54
0
47
16
0
16
16
16
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
16
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% I
% Lys:
0
0
0
0
8
0
0
8
0
8
0
0
8
0
16
% K
% Leu:
8
8
0
8
0
0
0
0
0
8
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
8
% M
% Asn:
0
0
0
0
0
8
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
8
8
8
0
0
0
0
0
62
0
8
% P
% Gln:
0
8
0
0
0
0
0
0
8
0
0
0
16
0
0
% Q
% Arg:
0
0
0
16
0
0
0
0
0
8
0
8
0
8
0
% R
% Ser:
8
8
0
0
0
24
8
54
8
0
8
8
0
0
0
% S
% Thr:
0
0
0
0
0
31
0
0
0
16
54
0
0
0
0
% T
% Val:
8
0
0
8
0
0
0
0
8
8
8
24
0
24
62
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _