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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UPF2
All Species:
30.61
Human Site:
S1191
Identified Species:
56.11
UniProt:
Q9HAU5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAU5
NP_056357.1
1272
147810
S1191
K
I
L
N
V
P
M
S
S
Q
L
A
A
N
H
Chimpanzee
Pan troglodytes
XP_507656
1448
165981
S1367
K
I
L
N
V
P
M
S
S
Q
L
A
A
N
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_857902
1271
147822
S1190
K
I
L
N
V
P
M
S
S
Q
L
A
A
N
H
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074601
1269
147534
S1188
K
I
L
N
V
P
M
S
S
Q
L
A
A
N
H
Rat
Rattus norvegicus
NP_001101891
1268
147324
S1187
K
I
L
N
V
P
M
S
S
Q
L
A
A
N
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417288
1272
147721
S1191
K
I
L
N
V
P
M
S
S
Q
L
A
A
N
H
Frog
Xenopus laevis
NP_001089661
1264
146847
S1183
K
I
L
N
V
P
M
S
S
Q
L
A
A
N
H
Zebra Danio
Brachydanio rerio
XP_697460
594
68181
K523
Y
F
D
R
G
S
S
K
K
K
L
D
C
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572434
1241
140038
A1162
Q
Q
F
K
S
F
V
A
P
S
D
S
H
L
A
Honey Bee
Apis mellifera
XP_396597
1132
130343
S1053
K
N
L
A
V
P
V
S
S
E
L
A
M
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002315268
1194
135972
D1105
K
Q
M
Y
I
P
R
D
C
S
L
V
Q
S
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181459
1181
133943
D1095
R
Q
M
L
I
P
S
D
C
A
L
V
Q
S
T
Baker's Yeast
Sacchar. cerevisiae
P38798
1089
126729
E1018
P
L
L
L
K
K
S
E
E
P
S
S
S
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
N.A.
97.7
N.A.
96.9
97
N.A.
N.A.
93.2
86.4
40
N.A.
36.3
45.5
N.A.
N.A.
Protein Similarity:
100
87.7
N.A.
99
N.A.
98.7
98.6
N.A.
N.A.
97.4
93.2
44.2
N.A.
56
62.8
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
6.6
N.A.
0
60
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
13.3
N.A.
26.6
73.3
N.A.
N.A.
Percent
Protein Identity:
37.1
N.A.
N.A.
34.4
21.3
N.A.
Protein Similarity:
54.2
N.A.
N.A.
53
40.9
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
40
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
8
0
8
0
62
54
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
16
0
0
0
8
0
0
% C
% Asp:
0
0
8
0
0
0
0
16
0
0
8
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
8
% E
% Phe:
0
8
8
0
0
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
54
% H
% Ile:
0
54
0
0
16
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
70
0
0
8
8
8
0
8
8
8
0
0
0
8
0
% K
% Leu:
0
8
70
16
0
0
0
0
0
0
85
0
0
8
16
% L
% Met:
0
0
16
0
0
0
54
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
54
0
0
0
0
0
0
0
0
0
62
0
% N
% Pro:
8
0
0
0
0
77
0
0
8
8
0
0
0
0
0
% P
% Gln:
8
24
0
0
0
0
0
0
0
54
0
0
16
0
0
% Q
% Arg:
8
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
24
62
62
16
8
16
8
16
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% T
% Val:
0
0
0
0
62
0
16
0
0
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _