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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UPF2
All Species:
21.52
Human Site:
T500
Identified Species:
39.44
UniProt:
Q9HAU5
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAU5
NP_056357.1
1272
147810
T500
K
E
S
N
K
D
D
T
K
E
A
K
E
S
K
Chimpanzee
Pan troglodytes
XP_507656
1448
165981
T676
K
E
S
N
K
D
D
T
K
E
T
K
E
S
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_857902
1271
147822
S499
K
D
S
N
K
D
D
S
K
E
A
K
E
P
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074601
1269
147534
S498
K
D
S
N
K
D
D
S
K
E
A
K
E
P
K
Rat
Rattus norvegicus
NP_001101891
1268
147324
S498
K
D
S
S
K
D
D
S
K
E
A
K
E
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417288
1272
147721
S499
K
D
A
S
K
D
E
S
R
D
S
K
D
A
K
Frog
Xenopus laevis
NP_001089661
1264
146847
G492
S
S
Q
S
K
E
T
G
K
D
N
V
K
D
T
Zebra Danio
Brachydanio rerio
XP_697460
594
68181
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572434
1241
140038
E441
I
D
A
N
L
D
A
E
M
D
L
D
D
P
P
Honey Bee
Apis mellifera
XP_396597
1132
130343
N441
A
F
I
T
H
L
P
N
C
V
N
R
E
L
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002315268
1194
135972
E435
T
E
K
G
K
D
K
E
E
K
D
K
E
K
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181459
1181
133943
K432
K
E
K
E
E
V
E
K
E
K
A
K
D
T
K
Baker's Yeast
Sacchar. cerevisiae
P38798
1089
126729
P427
T
Q
D
W
S
K
L
P
V
Y
S
R
F
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
N.A.
97.7
N.A.
96.9
97
N.A.
N.A.
93.2
86.4
40
N.A.
36.3
45.5
N.A.
N.A.
Protein Similarity:
100
87.7
N.A.
99
N.A.
98.7
98.6
N.A.
N.A.
97.4
93.2
44.2
N.A.
56
62.8
N.A.
N.A.
P-Site Identity:
100
93.3
N.A.
80
N.A.
80
73.3
N.A.
N.A.
33.3
13.3
0
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
93.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
N.A.
100
40
0
N.A.
40
13.3
N.A.
N.A.
Percent
Protein Identity:
37.1
N.A.
N.A.
34.4
21.3
N.A.
Protein Similarity:
54.2
N.A.
N.A.
53
40.9
N.A.
P-Site Identity:
33.3
N.A.
N.A.
33.3
0
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
73.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
0
0
0
8
0
0
0
39
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
39
8
0
0
62
39
0
0
24
8
8
24
8
0
% D
% Glu:
0
31
0
8
8
8
16
16
16
39
0
0
54
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% I
% Lys:
54
0
16
0
62
8
8
8
47
16
0
62
8
8
54
% K
% Leu:
0
0
0
0
8
8
8
0
0
0
8
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
39
0
0
0
8
0
0
16
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
8
8
0
0
0
0
0
31
8
% P
% Gln:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
16
0
0
0
% R
% Ser:
8
8
39
24
8
0
0
31
0
0
16
0
0
16
0
% S
% Thr:
16
0
0
8
0
0
8
16
0
0
8
0
0
8
8
% T
% Val:
0
0
0
0
0
8
0
0
8
8
0
8
0
0
8
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _