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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UPF2
All Species:
37.88
Human Site:
Y774
Identified Species:
69.44
UniProt:
Q9HAU5
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAU5
NP_056357.1
1272
147810
Y774
K
R
P
P
L
Q
E
Y
V
R
K
L
L
Y
K
Chimpanzee
Pan troglodytes
XP_507656
1448
165981
Y950
K
R
P
P
L
Q
E
Y
V
R
K
L
L
Y
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_857902
1271
147822
Y773
K
R
P
P
L
Q
E
Y
V
R
K
L
L
Y
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_001074601
1269
147534
Y772
K
R
P
P
L
Q
E
Y
V
R
K
L
L
Y
K
Rat
Rattus norvegicus
NP_001101891
1268
147324
Y772
K
R
P
P
L
Q
E
Y
V
R
K
L
L
Y
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417288
1272
147721
Y774
K
R
P
P
L
Q
E
Y
I
R
K
L
L
Y
K
Frog
Xenopus laevis
NP_001089661
1264
146847
Y766
K
R
P
P
L
Q
E
Y
I
R
K
L
L
Y
K
Zebra Danio
Brachydanio rerio
XP_697460
594
68181
R165
Q
L
P
N
C
I
N
R
D
L
I
D
K
A
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572434
1241
140038
Y717
V
R
P
A
M
H
E
Y
I
R
Y
L
I
F
E
Honey Bee
Apis mellifera
XP_396597
1132
130343
V692
K
Y
L
N
I
R
C
V
G
S
L
L
A
G
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002315268
1194
135972
Y679
V
R
P
P
L
Y
Q
Y
I
R
K
L
L
F
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_181459
1181
133943
Y672
V
R
P
P
L
H
Q
Y
V
R
K
L
L
F
S
Baker's Yeast
Sacchar. cerevisiae
P38798
1089
126729
R660
Q
V
L
E
N
I
E
R
G
L
E
I
N
D
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.7
N.A.
97.7
N.A.
96.9
97
N.A.
N.A.
93.2
86.4
40
N.A.
36.3
45.5
N.A.
N.A.
Protein Similarity:
100
87.7
N.A.
99
N.A.
98.7
98.6
N.A.
N.A.
97.4
93.2
44.2
N.A.
56
62.8
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
6.6
N.A.
40
13.3
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
N.A.
100
100
13.3
N.A.
73.3
26.6
N.A.
N.A.
Percent
Protein Identity:
37.1
N.A.
N.A.
34.4
21.3
N.A.
Protein Similarity:
54.2
N.A.
N.A.
53
40.9
N.A.
P-Site Identity:
60
N.A.
N.A.
66.6
6.6
N.A.
P-Site Similarity:
80
N.A.
N.A.
80
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
8
0
8
0
% D
% Glu:
0
0
0
8
0
0
70
0
0
0
8
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
0
% F
% Gly:
0
0
0
0
0
0
0
0
16
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
16
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
16
0
0
31
0
8
8
8
0
0
% I
% Lys:
62
0
0
0
0
0
0
0
0
0
70
0
8
0
54
% K
% Leu:
0
8
16
0
70
0
0
0
0
16
8
85
70
0
8
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
8
0
8
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
85
70
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
0
0
0
0
54
16
0
0
0
0
0
0
0
0
% Q
% Arg:
0
77
0
0
0
8
0
16
0
77
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
16
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
24
8
0
0
0
0
0
8
47
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
77
0
0
8
0
0
54
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _