Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UPF2 All Species: 37.88
Human Site: Y774 Identified Species: 69.44
UniProt: Q9HAU5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAU5 NP_056357.1 1272 147810 Y774 K R P P L Q E Y V R K L L Y K
Chimpanzee Pan troglodytes XP_507656 1448 165981 Y950 K R P P L Q E Y V R K L L Y K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_857902 1271 147822 Y773 K R P P L Q E Y V R K L L Y K
Cat Felis silvestris
Mouse Mus musculus NP_001074601 1269 147534 Y772 K R P P L Q E Y V R K L L Y K
Rat Rattus norvegicus NP_001101891 1268 147324 Y772 K R P P L Q E Y V R K L L Y K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417288 1272 147721 Y774 K R P P L Q E Y I R K L L Y K
Frog Xenopus laevis NP_001089661 1264 146847 Y766 K R P P L Q E Y I R K L L Y K
Zebra Danio Brachydanio rerio XP_697460 594 68181 R165 Q L P N C I N R D L I D K A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572434 1241 140038 Y717 V R P A M H E Y I R Y L I F E
Honey Bee Apis mellifera XP_396597 1132 130343 V692 K Y L N I R C V G S L L A G L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002315268 1194 135972 Y679 V R P P L Y Q Y I R K L L F S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_181459 1181 133943 Y672 V R P P L H Q Y V R K L L F S
Baker's Yeast Sacchar. cerevisiae P38798 1089 126729 R660 Q V L E N I E R G L E I N D Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87.7 N.A. 97.7 N.A. 96.9 97 N.A. N.A. 93.2 86.4 40 N.A. 36.3 45.5 N.A. N.A.
Protein Similarity: 100 87.7 N.A. 99 N.A. 98.7 98.6 N.A. N.A. 97.4 93.2 44.2 N.A. 56 62.8 N.A. N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 93.3 93.3 6.6 N.A. 40 13.3 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. N.A. 100 100 13.3 N.A. 73.3 26.6 N.A. N.A.
Percent
Protein Identity: 37.1 N.A. N.A. 34.4 21.3 N.A.
Protein Similarity: 54.2 N.A. N.A. 53 40.9 N.A.
P-Site Identity: 60 N.A. N.A. 66.6 6.6 N.A.
P-Site Similarity: 80 N.A. N.A. 80 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 0 0 0 8 8 8 % A
% Cys: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 8 0 8 0 % D
% Glu: 0 0 0 8 0 0 70 0 0 0 8 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 24 0 % F
% Gly: 0 0 0 0 0 0 0 0 16 0 0 0 0 8 0 % G
% His: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 16 0 0 31 0 8 8 8 0 0 % I
% Lys: 62 0 0 0 0 0 0 0 0 0 70 0 8 0 54 % K
% Leu: 0 8 16 0 70 0 0 0 0 16 8 85 70 0 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 16 8 0 8 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 85 70 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 16 0 0 0 0 54 16 0 0 0 0 0 0 0 0 % Q
% Arg: 0 77 0 0 0 8 0 16 0 77 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 16 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 24 8 0 0 0 0 0 8 47 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 0 77 0 0 8 0 0 54 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _