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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 20.61
Human Site: S37 Identified Species: 37.78
UniProt: Q9HAU6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAU6 NP_003286 173 20263 S37 E V E Q K M L S K T T G N T D
Chimpanzee Pan troglodytes XP_001146432 172 19563 S37 E V E G K M V S R T E G N I D
Rhesus Macaque Macaca mulatta XP_001112392 172 19576 S37 E V E G K M V S R T E G N I D
Dog Lupus familis XP_856393 133 15058 H10 I Y R D L I S H D E M F S D I
Cat Felis silvestris
Mouse Mus musculus NP_033455 172 19444 S37 E V E G K M V S R T E G A I D
Rat Rattus norvegicus P63029 172 19444 S37 E V E G K M V S R T E G A I D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P43347 172 19512 T37 E V E G K M V T R T E G Q I D
Frog Xenopus laevis Q7ZYF2 172 19508 Q37 E V E G K V I Q R E E G A I D
Zebra Danio Brachydanio rerio Q9DGK4 171 19006 T37 E V E G K M I T R A E G D I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGS2 172 19619 R37 V Y G K L I T R Q G D D I K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays Q8H6A5 167 18672 W35 L W E V E G K W V T Q G P V D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35691 167 18723 N36 E A D C A M V N V G G D N I D
Red Bread Mold Neurospora crassa Q7RYV5 170 19009 E37 V D C A M I E E G A V Q V D I
Conservation
Percent
Protein Identity: 100 72.2 72.2 58.3 N.A. 69.9 69.9 N.A. N.A. 66.4 52.5 49.7 N.A. 40.4 N.A. N.A. N.A.
Protein Similarity: 100 83.8 84.3 66.4 N.A. 83.2 83.2 N.A. N.A. 82 72.2 71.6 N.A. 65.3 N.A. N.A. N.A.
P-Site Identity: 100 66.6 66.6 0 N.A. 60 60 N.A. N.A. 53.3 40 46.6 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 80 80 13.3 N.A. 73.3 73.3 N.A. N.A. 73.3 60 73.3 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. 36.4 N.A. N.A. 32.9 35.2
Protein Similarity: N.A. 55.4 N.A. N.A. 60.1 60.6
P-Site Identity: N.A. 26.6 N.A. N.A. 26.6 0
P-Site Similarity: N.A. 33.3 N.A. N.A. 46.6 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 8 0 0 0 0 16 0 0 24 0 0 % A
% Cys: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 8 0 0 0 0 8 0 8 16 8 16 77 % D
% Glu: 70 0 70 0 8 0 8 8 0 16 54 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 8 54 0 8 0 0 8 16 8 70 0 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 24 16 0 0 0 0 0 8 62 16 % I
% Lys: 0 0 0 8 62 0 8 0 8 0 0 0 0 8 0 % K
% Leu: 8 0 0 0 16 0 8 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 8 62 0 0 0 0 8 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 31 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 8 0 0 0 8 8 0 8 8 8 0 0 % Q
% Arg: 0 0 8 0 0 0 0 8 54 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 8 39 0 0 0 0 8 0 0 % S
% Thr: 0 0 0 0 0 0 8 16 0 54 8 0 0 8 0 % T
% Val: 16 62 0 8 0 8 47 0 16 0 8 0 8 8 0 % V
% Trp: 0 8 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _