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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GNB4
All Species:
46.67
Human Site:
S221
Identified Species:
73.33
UniProt:
Q9HAV0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAV0
NP_067642.1
340
37567
S221
R
D
G
M
C
R
Q
S
F
T
G
H
V
S
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545211
340
37563
S221
R
D
G
M
C
R
Q
S
F
T
G
H
V
S
D
Cat
Felis silvestris
Mouse
Mus musculus
P29387
340
37361
S221
R
D
G
M
C
R
Q
S
F
T
G
H
I
S
D
Rat
Rattus norvegicus
O35353
340
37345
S221
R
D
G
M
C
R
Q
S
F
T
G
H
I
S
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505530
340
37558
S221
R
D
G
M
C
R
Q
S
F
T
G
H
V
S
D
Chicken
Gallus gallus
NP_001012853
404
44596
T221
R
E
G
M
C
R
Q
T
F
T
G
H
E
S
D
Frog
Xenopus laevis
P79959
340
37311
T221
R
E
G
M
C
R
Q
T
F
T
G
H
E
S
D
Zebra Danio
Brachydanio rerio
Q6PH57
340
37267
T221
R
E
G
M
C
R
Q
T
F
T
G
H
E
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P26308
340
37114
T221
R
E
G
V
C
K
Q
T
F
P
G
H
E
S
D
Honey Bee
Apis mellifera
XP_393976
341
37351
T222
R
E
G
T
C
K
Q
T
F
P
G
H
E
S
D
Nematode Worm
Caenorhab. elegans
P17343
340
37388
T221
R
D
G
M
C
K
Q
T
F
P
G
H
E
S
D
Sea Urchin
Strong. purpuratus
XP_001176793
341
37543
T222
R
E
G
M
C
K
Q
T
F
T
G
H
E
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P49178
380
41696
L232
S
C
D
T
T
V
R
L
W
D
I
R
I
A
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P49177
377
40987
L231
S
C
D
S
T
A
R
L
W
D
T
R
A
A
S
Baker's Yeast
Sacchar. cerevisiae
P18851
423
46563
R258
Y
T
Y
I
W
D
S
R
S
P
S
A
V
Q
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.7
N.A.
96.7
97
N.A.
95.5
75.7
90.8
90.8
N.A.
81.7
85.3
84.7
86.5
Protein Similarity:
100
N.A.
N.A.
100
N.A.
98.8
98.8
N.A.
98.8
80.1
96.1
95.8
N.A.
92.9
93.5
93.8
94.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
93.3
N.A.
100
80
80
80
N.A.
60
60
73.3
73.3
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
100
93.3
93.3
93.3
N.A.
86.6
80
86.6
93.3
Percent
Protein Identity:
N.A.
42.8
N.A.
44.5
33.1
N.A.
Protein Similarity:
N.A.
61.8
N.A.
62.8
50.3
N.A.
P-Site Identity:
N.A.
0
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
0
0
0
7
7
14
0
% A
% Cys:
0
14
0
0
80
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
40
14
0
0
7
0
0
0
14
0
0
0
0
80
% D
% Glu:
0
40
0
0
0
0
0
0
0
0
0
0
47
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
80
0
0
0
0
0
0
% F
% Gly:
0
0
80
0
0
0
0
0
0
0
80
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
80
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
7
0
20
0
0
% I
% Lys:
0
0
0
0
0
27
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
14
0
0
0
0
0
0
0
% L
% Met:
0
0
0
67
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
27
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
80
0
0
0
0
0
0
7
0
% Q
% Arg:
80
0
0
0
0
54
14
7
0
0
0
14
0
0
0
% R
% Ser:
14
0
0
7
0
0
7
34
7
0
7
0
0
80
20
% S
% Thr:
0
7
0
14
14
0
0
47
0
60
7
0
0
0
0
% T
% Val:
0
0
0
7
0
7
0
0
0
0
0
0
27
0
0
% V
% Trp:
0
0
0
0
7
0
0
0
14
0
0
0
0
0
0
% W
% Tyr:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _