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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GRPEL1 All Species: 27.88
Human Site: T181 Identified Species: 43.81
UniProt: Q9HAV7 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAV7 NP_079472.1 217 24279 T181 E H E A L F H T P V E G K E P
Chimpanzee Pan troglodytes XP_001163063 225 25422 P185 H E L I C H V P A G V G V Q P
Rhesus Macaque Macaca mulatta XP_001091412 217 24229 T181 E H E A L F H T P V E G K E P
Dog Lupus familis XP_545902 294 32000 T258 E H E A L F H T P V E G K E P
Cat Felis silvestris
Mouse Mus musculus Q99LP6 217 24289 T181 E H E A L F H T P V E G K E P
Rat Rattus norvegicus P97576 217 24279 T181 E H E A L F H T P V E G K E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521091 285 31001 T249 E H E A L F H T P V E G K E P
Chicken Gallus gallus NP_001006458 222 24822 A186 E H E A L F H A P M E G K E P
Frog Xenopus laevis NP_001089487 216 24086 S180 E H E A L F H S P V A G K E P
Zebra Danio Brachydanio rerio NP_001032461 217 23858 A181 E H E A V F H A P V E G K E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48604 213 23908 K178 Q H E A L F Q K E D K T V E P
Honey Bee Apis mellifera XP_624159 232 26421 Q197 Q H E A L F Q Q E V E G K E P
Nematode Worm Caenorhab. elegans Q18421 237 26430 S202 E A V F Q I P S A N A K Q P V
Sea Urchin Strong. purpuratus XP_798953 168 18775 K137 F Q I P V P D K E P G T V A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q9P5U4 238 26809 A202 E H E A T F M A P M P D K E H
Conservation
Percent
Protein Identity: 100 41.3 99.5 66.6 N.A. 88 88.4 N.A. 65.2 80.1 69.1 72.8 N.A. 44.7 49.1 35.8 49.3
Protein Similarity: 100 64 100 71 N.A. 95.3 95.3 N.A. 71.2 88.7 82.4 82.4 N.A. 60.8 64.2 55.7 58
P-Site Identity: 100 13.3 100 100 N.A. 100 100 N.A. 100 86.6 86.6 86.6 N.A. 46.6 73.3 6.6 0
P-Site Similarity: 100 20 100 100 N.A. 100 100 N.A. 100 93.3 93.3 93.3 N.A. 60 80 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 37.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 53.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 53.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 80 0 0 0 20 14 0 14 0 0 7 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 7 0 0 7 0 7 0 0 0 % D
% Glu: 74 7 80 0 0 0 0 0 20 0 60 0 0 80 0 % E
% Phe: 7 0 0 7 0 80 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 7 7 74 0 0 0 % G
% His: 7 80 0 0 0 7 60 0 0 0 0 0 0 0 7 % H
% Ile: 0 0 7 7 0 7 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 14 0 0 7 7 74 0 0 % K
% Leu: 0 0 7 0 67 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 14 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % N
% Pro: 0 0 0 7 0 7 7 7 67 7 7 0 0 7 80 % P
% Gln: 14 7 0 0 7 0 14 7 0 0 0 0 7 7 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 14 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 7 0 0 40 0 0 0 14 0 0 0 % T
% Val: 0 0 7 0 14 0 7 0 0 60 7 0 20 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _