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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UGT1A8 All Species: 13.64
Human Site: T335 Identified Species: 75
UniProt: Q9HAW9 Number Species: 4
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAW9 NP_061949.3 530 59742 T335 Q T V L W R Y T G T R P S N L
Chimpanzee Pan troglodytes XP_001151168 532 60662 T337 Q T V L W R Y T G T R P S N L
Rhesus Macaque Macaca mulatta Q9GLD9 529 60840 D340 Q K V L W R F D G N K P D T L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q62452 528 59989 T333 Q T V L W R Y T G T R P S N L
Rat Rattus norvegicus Q64634 530 60042 T335 Q T L L W R Y T G T R P S N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.3 45.4 N.A. N.A. 79.2 78.1 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 77.8 62.6 N.A. N.A. 87.3 86.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 53.3 N.A. N.A. 100 93.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 66.6 N.A. N.A. 100 100 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 20 0 0 0 0 20 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 20 0 0 0 0 0 0 0 0 20 0 0 0 0 % K
% Leu: 0 0 20 100 0 0 0 0 0 0 0 0 0 0 100 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 20 0 0 0 80 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % P
% Gln: 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 100 0 0 0 0 80 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 80 0 0 % S
% Thr: 0 80 0 0 0 0 0 80 0 80 0 0 0 20 0 % T
% Val: 0 0 80 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _