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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK4
All Species:
19.09
Human Site:
S104
Identified Species:
35
UniProt:
Q9HAZ1
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAZ1
NP_065717.1
481
57492
S104
Y
R
I
H
C
S
K
S
S
V
R
S
R
R
S
Chimpanzee
Pan troglodytes
XP_001148409
445
52800
E104
R
K
R
S
R
S
I
E
D
D
E
E
G
H
L
Rhesus Macaque
Macaca mulatta
XP_001097751
481
57494
S104
Y
R
I
H
C
S
K
S
S
V
R
S
R
R
S
Dog
Lupus familis
XP_531875
481
57271
S104
Y
R
V
H
C
S
K
S
S
V
R
S
R
R
S
Cat
Felis silvestris
Mouse
Mus musculus
O35493
481
57326
S104
Y
R
I
H
C
S
K
S
S
V
R
S
R
R
S
Rat
Rattus norvegicus
Q63117
490
58467
S119
K
R
R
T
R
S
C
S
S
A
S
S
R
S
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505282
480
57495
S104
Y
Y
D
C
S
K
S
S
G
R
S
R
R
S
S
Chicken
Gallus gallus
Q5ZIU3
526
59419
T104
H
N
E
I
F
G
Y
T
E
I
Y
F
L
G
P
Frog
Xenopus laevis
NP_001091432
462
54946
S104
R
H
R
K
H
H
H
S
R
H
T
S
P
S
K
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
Y132
D
R
D
R
E
D
S
Y
R
R
K
G
S
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
I424
L
Q
Q
S
N
S
V
I
F
N
H
S
G
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
M104
R
Y
K
I
Y
S
K
M
G
E
G
T
F
G
Q
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
E233
G
S
C
A
K
T
L
E
G
N
K
A
V
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
99.3
98.1
N.A.
97
52
N.A.
90.8
22
68.1
53.4
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
91.4
99.7
99.1
N.A.
98.5
66.7
N.A.
94.1
39.1
78.5
68
N.A.
43.7
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
93.3
N.A.
100
40
N.A.
26.6
0
13.3
13.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
40
N.A.
26.6
20
13.3
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.7
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.2
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% A
% Cys:
0
0
8
8
31
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
0
8
0
0
8
8
0
0
0
0
0
% D
% Glu:
0
0
8
0
8
0
0
16
8
8
8
8
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
0
8
8
0
0
% F
% Gly:
8
0
0
0
0
8
0
0
24
0
8
8
16
16
0
% G
% His:
8
8
0
31
8
8
8
0
0
8
8
0
0
8
0
% H
% Ile:
0
0
24
16
0
0
8
8
0
8
0
0
0
0
0
% I
% Lys:
8
8
8
8
8
8
39
0
0
0
16
0
0
0
8
% K
% Leu:
8
0
0
0
0
0
8
0
0
0
0
0
8
0
16
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
16
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% P
% Gln:
0
8
8
0
0
0
0
0
0
0
0
0
0
8
24
% Q
% Arg:
24
47
24
8
16
0
0
0
16
16
31
8
47
39
8
% R
% Ser:
0
8
0
16
8
62
16
54
39
0
16
54
8
24
39
% S
% Thr:
0
0
0
8
0
8
0
8
0
0
8
8
0
0
0
% T
% Val:
0
0
8
0
0
0
8
0
0
31
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
39
16
0
0
8
0
8
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _