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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLK4
All Species:
30.61
Human Site:
Y299
Identified Species:
56.11
UniProt:
Q9HAZ1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAZ1
NP_065717.1
481
57492
Y299
I
L
F
V
K
S
D
Y
V
V
K
Y
N
S
K
Chimpanzee
Pan troglodytes
XP_001148409
445
52800
S269
D
Y
V
V
K
Y
N
S
K
M
K
R
D
E
R
Rhesus Macaque
Macaca mulatta
XP_001097751
481
57494
Y299
I
L
F
V
K
S
D
Y
V
V
K
Y
N
S
K
Dog
Lupus familis
XP_531875
481
57271
Y299
I
L
F
V
K
S
D
Y
V
V
K
Y
N
S
K
Cat
Felis silvestris
Mouse
Mus musculus
O35493
481
57326
Y299
I
L
F
V
K
S
D
Y
V
V
K
Y
N
S
K
Rat
Rattus norvegicus
Q63117
490
58467
F296
I
L
F
V
N
S
E
F
E
T
L
Y
N
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505282
480
57495
Y298
I
L
F
V
K
S
D
Y
V
V
K
Y
N
S
K
Chicken
Gallus gallus
Q5ZIU3
526
59419
R286
I
L
L
K
Q
Q
G
R
S
G
I
K
V
I
D
Frog
Xenopus laevis
NP_001091432
462
54946
Y281
I
L
F
V
H
S
D
Y
V
V
N
F
N
P
T
Zebra Danio
Brachydanio rerio
NP_001038344
526
62655
Y327
I
L
F
V
N
S
D
Y
T
V
T
Y
N
V
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49762
832
95705
Y618
I
L
F
V
D
S
D
Y
T
S
H
Y
N
H
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
S269
I
K
V
I
D
F
G
S
T
T
Y
E
R
Q
D
Baker's Yeast
Sacchar. cerevisiae
P32350
737
83824
L466
P
L
K
T
V
Q
S
L
S
K
R
R
R
E
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
99.3
98.1
N.A.
97
52
N.A.
90.8
22
68.1
53.4
N.A.
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
91.4
99.7
99.1
N.A.
98.5
66.7
N.A.
94.1
39.1
78.5
68
N.A.
43.7
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
100
N.A.
100
46.6
N.A.
100
13.3
66.6
66.6
N.A.
66.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
100
N.A.
100
60
N.A.
100
20
73.3
73.3
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.7
26.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.2
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
16
0
62
0
0
0
0
0
8
0
16
% D
% Glu:
0
0
0
0
0
0
8
0
8
0
0
8
0
24
8
% E
% Phe:
0
0
70
0
0
8
0
8
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
16
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
0
8
8
% H
% Ile:
85
0
0
8
0
0
0
0
0
0
8
0
0
8
0
% I
% Lys:
0
8
8
8
47
0
0
0
8
8
47
8
0
0
47
% K
% Leu:
0
85
8
0
0
0
0
8
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
16
0
8
0
0
0
8
0
70
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
16
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
8
16
16
0
8
% R
% Ser:
0
0
0
0
0
70
8
16
16
8
0
0
0
39
0
% S
% Thr:
0
0
0
8
0
0
0
0
24
16
8
0
0
0
8
% T
% Val:
0
0
16
77
8
0
0
0
47
54
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
8
0
62
0
0
8
62
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _