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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDM16 All Species: 13.33
Human Site: S477 Identified Species: 26.67
UniProt: Q9HAZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAZ2 NP_071397.2 1276 140251 S477 D K A K P S P S L N H A S L G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093583 1230 138131 M459 D K T S M V N M S H A N P G L
Dog Lupus familis XP_536720 1330 145448 T552 D K A K P P P T L N H T S L G
Cat Felis silvestris
Mouse Mus musculus A2A935 1275 140840 T478 D K T K P S P T L N H G G L G
Rat Rattus norvegicus XP_002726668 1257 138805 T478 D K T K P S P T L N H G G L G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508323 979 106177 C234 P C F R S Q G C L G H R H H S
Chicken Gallus gallus XP_417551 908 100815 A163 T W L K Y I R A A C S C A E Q
Frog Xenopus laevis B7ZRU9 1055 118966 S310 S F P G L F P S S L Y H R P P
Zebra Danio Brachydanio rerio XP_001922927 1153 129171 A408 D A P A L S V A S S M N N S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8I7Z8 990 109209 H245 D H L I G A H H F K Q D E F P
Honey Bee Apis mellifera XP_001121599 1541 171480 S518 V Y P R P P V S L P G G L P F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798234 1723 193143 R957 K R M H A N C R T Q L K C A T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 53.9 83.4 N.A. 88.2 86.2 N.A. 57.1 59.9 45.4 61.2 N.A. 27.5 21.8 N.A. 20.8
Protein Similarity: 100 N.A. 68 87.8 N.A. 91.8 90.1 N.A. 62.1 64.5 57.2 71.9 N.A. 39.9 35.3 N.A. 35.8
P-Site Identity: 100 N.A. 13.3 80 N.A. 73.3 73.3 N.A. 13.3 6.6 13.3 13.3 N.A. 6.6 20 N.A. 0
P-Site Similarity: 100 N.A. 20 86.6 N.A. 80 80 N.A. 20 20 20 33.3 N.A. 13.3 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 9 9 9 0 17 9 0 9 9 9 9 0 % A
% Cys: 0 9 0 0 0 0 9 9 0 9 0 9 9 0 0 % C
% Asp: 59 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 9 9 0 % E
% Phe: 0 9 9 0 0 9 0 0 9 0 0 0 0 9 9 % F
% Gly: 0 0 0 9 9 0 9 0 0 9 9 25 17 9 34 % G
% His: 0 9 0 9 0 0 9 9 0 9 42 9 9 9 0 % H
% Ile: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 42 0 42 0 0 0 0 0 9 0 9 0 0 0 % K
% Leu: 0 0 17 0 17 0 0 0 50 9 9 0 9 34 9 % L
% Met: 0 0 9 0 9 0 0 9 0 0 9 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 9 0 0 34 0 17 9 0 9 % N
% Pro: 9 0 25 0 42 17 42 0 0 9 0 0 9 17 17 % P
% Gln: 0 0 0 0 0 9 0 0 0 9 9 0 0 0 9 % Q
% Arg: 0 9 0 17 0 0 9 9 0 0 0 9 9 0 0 % R
% Ser: 9 0 0 9 9 34 0 25 25 9 9 0 17 9 9 % S
% Thr: 9 0 25 0 0 0 0 25 9 0 0 9 0 0 9 % T
% Val: 9 0 0 0 0 9 17 0 0 0 0 0 0 0 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 9 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _