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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDM16 All Species: 6.36
Human Site: T219 Identified Species: 12.73
UniProt: Q9HAZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAZ2 NP_071397.2 1276 140251 T219 E G V Y P L G T V P P G L D E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093583 1230 138131 T198 S E D Y P H E T M A P D I H E
Dog Lupus familis XP_536720 1330 145448 T293 E G A Y S L G T V P P S L D E
Cat Felis silvestris
Mouse Mus musculus A2A935 1275 140840 V219 E G A Y S L G V M A P S L D E
Rat Rattus norvegicus XP_002726668 1257 138805 V219 E G A Y S L G V M A P S L D E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508323 979 106177
Chicken Gallus gallus XP_417551 908 100815
Frog Xenopus laevis B7ZRU9 1055 118966 N56 S A F S L V E N S F P P S L N
Zebra Danio Brachydanio rerio XP_001922927 1153 129171 T154 G Q H M I V H T E E R E Y K C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8I7Z8 990 109209
Honey Bee Apis mellifera XP_001121599 1541 171480 E256 I G G Q M V Y E A V R D I A A
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798234 1723 193143 L402 K M E T F S Q L L K R L V F S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 53.9 83.4 N.A. 88.2 86.2 N.A. 57.1 59.9 45.4 61.2 N.A. 27.5 21.8 N.A. 20.8
Protein Similarity: 100 N.A. 68 87.8 N.A. 91.8 90.1 N.A. 62.1 64.5 57.2 71.9 N.A. 39.9 35.3 N.A. 35.8
P-Site Identity: 100 N.A. 33.3 80 N.A. 60 60 N.A. 0 0 6.6 6.6 N.A. 0 6.6 N.A. 0
P-Site Similarity: 100 N.A. 46.6 80 N.A. 66.6 66.6 N.A. 0 0 13.3 13.3 N.A. 0 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 25 0 0 0 0 0 9 25 0 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 17 0 34 0 % D
% Glu: 34 9 9 0 0 0 17 9 9 9 0 9 0 0 42 % E
% Phe: 0 0 9 0 9 0 0 0 0 9 0 0 0 9 0 % F
% Gly: 9 42 9 0 0 0 34 0 0 0 0 9 0 0 0 % G
% His: 0 0 9 0 0 9 9 0 0 0 0 0 0 9 0 % H
% Ile: 9 0 0 0 9 0 0 0 0 0 0 0 17 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 0 9 0 0 0 9 0 % K
% Leu: 0 0 0 0 9 34 0 9 9 0 0 9 34 9 0 % L
% Met: 0 9 0 9 9 0 0 0 25 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % N
% Pro: 0 0 0 0 17 0 0 0 0 17 50 9 0 0 0 % P
% Gln: 0 9 0 9 0 0 9 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 25 0 0 0 0 % R
% Ser: 17 0 0 9 25 9 0 0 9 0 0 25 9 0 9 % S
% Thr: 0 0 0 9 0 0 0 34 0 0 0 0 0 0 0 % T
% Val: 0 0 9 0 0 25 0 17 17 9 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 42 0 0 9 0 0 0 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _