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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDM16 All Species: 13.33
Human Site: T464 Identified Species: 26.67
UniProt: Q9HAZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAZ2 NP_071397.2 1276 140251 T464 F A P G L P L T P S P M M D K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093583 1230 138131 P446 F G Q G I S L P G T P A M D K
Dog Lupus familis XP_536720 1330 145448 T539 F A P G L P L T A S P M M D K
Cat Felis silvestris
Mouse Mus musculus A2A935 1275 140840 T465 F T P G L P L T P S P M M D K
Rat Rattus norvegicus XP_002726668 1257 138805 T465 F T P G L P L T P S P M M D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508323 979 106177 D221 F P F C L V P D G S R P I P C
Chicken Gallus gallus XP_417551 908 100815 N150 E K F C I D A N Q S G A G T W
Frog Xenopus laevis B7ZRU9 1055 118966 A297 A G L T F P T A P G F P F S F
Zebra Danio Brachydanio rerio XP_001922927 1153 129171 G395 P L N N S Q D G K L P H L D A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8I7Z8 990 109209 D232 V C D K V Y P D L D L L D D H
Honey Bee Apis mellifera XP_001121599 1541 171480 A505 M P Q L P T P A P S P F L V Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798234 1723 193143 S944 L K S Y T Q F S N L C R H K R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 53.9 83.4 N.A. 88.2 86.2 N.A. 57.1 59.9 45.4 61.2 N.A. 27.5 21.8 N.A. 20.8
Protein Similarity: 100 N.A. 68 87.8 N.A. 91.8 90.1 N.A. 62.1 64.5 57.2 71.9 N.A. 39.9 35.3 N.A. 35.8
P-Site Identity: 100 N.A. 46.6 93.3 N.A. 93.3 93.3 N.A. 20 6.6 13.3 13.3 N.A. 6.6 20 N.A. 0
P-Site Similarity: 100 N.A. 60 93.3 N.A. 93.3 93.3 N.A. 26.6 13.3 13.3 20 N.A. 20 26.6 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 0 0 0 0 9 17 9 0 0 17 0 0 9 % A
% Cys: 0 9 0 17 0 0 0 0 0 0 9 0 0 0 9 % C
% Asp: 0 0 9 0 0 9 9 17 0 9 0 0 9 59 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 50 0 17 0 9 0 9 0 0 0 9 9 9 0 9 % F
% Gly: 0 17 0 42 0 0 0 9 17 9 9 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 9 % H
% Ile: 0 0 0 0 17 0 0 0 0 0 0 0 9 0 0 % I
% Lys: 0 17 0 9 0 0 0 0 9 0 0 0 0 9 42 % K
% Leu: 9 9 9 9 42 0 42 0 9 17 9 9 17 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 34 42 0 0 % M
% Asn: 0 0 9 9 0 0 0 9 9 0 0 0 0 0 0 % N
% Pro: 9 17 34 0 9 42 25 9 42 0 59 17 0 9 0 % P
% Gln: 0 0 17 0 0 17 0 0 9 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 9 9 0 0 9 % R
% Ser: 0 0 9 0 9 9 0 9 0 59 0 0 0 9 0 % S
% Thr: 0 17 0 9 9 9 9 34 0 9 0 0 0 9 0 % T
% Val: 9 0 0 0 9 9 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 9 0 9 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _