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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRDM16
All Species:
13.33
Human Site:
Y488
Identified Species:
26.67
UniProt:
Q9HAZ2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HAZ2
NP_071397.2
1276
140251
Y488
A
S
L
G
F
N
E
Y
F
P
S
R
P
H
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093583
1230
138131
F470
N
P
G
L
A
D
Y
F
G
A
N
R
H
P
A
Dog
Lupus familis
XP_536720
1330
145448
Y563
T
S
L
G
F
N
E
Y
F
P
S
R
P
H
P
Cat
Felis silvestris
Mouse
Mus musculus
A2A935
1275
140840
Y489
G
G
L
G
F
S
E
Y
F
P
S
R
P
H
P
Rat
Rattus norvegicus
XP_002726668
1257
138805
Y489
G
G
L
G
F
S
E
Y
F
P
S
R
P
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508323
979
106177
C245
R
H
H
S
S
S
A
C
R
M
Q
G
P
R
E
Chicken
Gallus gallus
XP_417551
908
100815
V174
C
A
E
Q
N
L
A
V
C
H
V
N
D
Q
I
Frog
Xenopus laevis
B7ZRU9
1055
118966
P321
H
R
P
P
F
I
P
P
A
S
P
V
K
G
L
Zebra Danio
Brachydanio rerio
XP_001922927
1153
129171
G419
N
N
S
N
G
N
I
G
S
S
L
S
S
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q8I7Z8
990
109209
C256
D
E
F
P
C
K
Q
C
A
L
R
F
C
H
R
Honey Bee
Apis mellifera
XP_001121599
1541
171480
S529
G
L
P
F
Y
P
T
S
L
M
G
P
Y
P
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798234
1723
193143
T968
K
C
A
T
C
G
Q
T
F
S
T
V
T
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
53.9
83.4
N.A.
88.2
86.2
N.A.
57.1
59.9
45.4
61.2
N.A.
27.5
21.8
N.A.
20.8
Protein Similarity:
100
N.A.
68
87.8
N.A.
91.8
90.1
N.A.
62.1
64.5
57.2
71.9
N.A.
39.9
35.3
N.A.
35.8
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
80
80
N.A.
6.6
0
6.6
6.6
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
N.A.
26.6
93.3
N.A.
86.6
86.6
N.A.
13.3
6.6
6.6
13.3
N.A.
13.3
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
9
0
17
0
17
9
0
0
0
0
9
% A
% Cys:
9
9
0
0
17
0
0
17
9
0
0
0
9
0
0
% C
% Asp:
9
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% D
% Glu:
0
9
9
0
0
0
34
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
9
9
42
0
0
9
42
0
0
9
0
0
0
% F
% Gly:
25
17
9
34
9
9
0
9
9
0
9
9
0
9
9
% G
% His:
9
9
9
0
0
0
0
0
0
9
0
0
9
42
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
9
% I
% Lys:
9
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% K
% Leu:
0
9
34
9
0
9
0
0
9
9
9
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% M
% Asn:
17
9
0
9
9
25
0
0
0
0
9
9
0
0
0
% N
% Pro:
0
9
17
17
0
9
9
9
0
34
9
9
42
17
34
% P
% Gln:
0
0
0
9
0
0
17
0
0
0
9
0
0
17
0
% Q
% Arg:
9
9
0
0
0
0
0
0
9
0
9
42
0
9
9
% R
% Ser:
0
17
9
9
9
25
0
9
9
25
34
9
9
9
9
% S
% Thr:
9
0
0
9
0
0
9
9
0
0
9
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
9
0
0
9
17
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
9
34
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _