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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRDM16 All Species: 14.55
Human Site: Y886 Identified Species: 29.09
UniProt: Q9HAZ2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HAZ2 NP_071397.2 1276 140251 Y886 V G A L K E K Y L R P S P L L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093583 1230 138131 S861 F L F H P Q M S A I E N M A E
Dog Lupus familis XP_536720 1330 145448 Y959 V G V L K E K Y L R P S P L L
Cat Felis silvestris
Mouse Mus musculus A2A935 1275 140840 Y886 V G V L K E K Y L R P S P L L
Rat Rattus norvegicus XP_002726668 1257 138805 Y887 V G V L K E K Y L R P S P L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508323 979 106177 R625 D S D V D S D R D K A K D K G
Chicken Gallus gallus XP_417551 908 100815 P554 N F P H S L Y P F T E R T L N
Frog Xenopus laevis B7ZRU9 1055 118966 E701 S F N A L K P E A N N L I Q S
Zebra Danio Brachydanio rerio XP_001922927 1153 129171 S799 L K L D A P N S L Q H S S H H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8I7Z8 990 109209 R636 P L D L S I C R K R S A G S F
Honey Bee Apis mellifera XP_001121599 1541 171480 K1100 P T L L H D P K Y P P A M R E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798234 1723 193143 G1365 K Y Q R M E N G E K V P A V P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 53.9 83.4 N.A. 88.2 86.2 N.A. 57.1 59.9 45.4 61.2 N.A. 27.5 21.8 N.A. 20.8
Protein Similarity: 100 N.A. 68 87.8 N.A. 91.8 90.1 N.A. 62.1 64.5 57.2 71.9 N.A. 39.9 35.3 N.A. 35.8
P-Site Identity: 100 N.A. 0 93.3 N.A. 93.3 93.3 N.A. 0 6.6 0 13.3 N.A. 13.3 13.3 N.A. 6.6
P-Site Similarity: 100 N.A. 13.3 93.3 N.A. 93.3 93.3 N.A. 13.3 6.6 6.6 26.6 N.A. 20 26.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 9 0 0 0 17 0 9 17 9 9 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 17 9 9 9 9 0 9 0 0 0 9 0 0 % D
% Glu: 0 0 0 0 0 42 0 9 9 0 17 0 0 0 17 % E
% Phe: 9 17 9 0 0 0 0 0 9 0 0 0 0 0 9 % F
% Gly: 0 34 0 0 0 0 0 9 0 0 0 0 9 0 9 % G
% His: 0 0 0 17 9 0 0 0 0 0 9 0 0 9 9 % H
% Ile: 0 0 0 0 0 9 0 0 0 9 0 0 9 0 0 % I
% Lys: 9 9 0 0 34 9 34 9 9 17 0 9 0 9 0 % K
% Leu: 9 17 17 50 9 9 0 0 42 0 0 9 0 42 34 % L
% Met: 0 0 0 0 9 0 9 0 0 0 0 0 17 0 0 % M
% Asn: 9 0 9 0 0 0 17 0 0 9 9 9 0 0 9 % N
% Pro: 17 0 9 0 9 9 17 9 0 9 42 9 34 0 9 % P
% Gln: 0 0 9 0 0 9 0 0 0 9 0 0 0 9 0 % Q
% Arg: 0 0 0 9 0 0 0 17 0 42 0 9 0 9 0 % R
% Ser: 9 9 0 0 17 9 0 17 0 0 9 42 9 9 9 % S
% Thr: 0 9 0 0 0 0 0 0 0 9 0 0 9 0 0 % T
% Val: 34 0 25 9 0 0 0 0 0 0 9 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 9 34 9 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _