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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C12orf10
All Species:
16.97
Human Site:
S281
Identified Species:
31.11
UniProt:
Q9HB07
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB07
NP_067653
376
42445
S281
E
H
L
Y
H
L
E
S
G
L
S
P
P
V
A
Chimpanzee
Pan troglodytes
XP_522402
376
42518
S281
E
H
L
Y
H
L
E
S
G
L
S
P
P
V
A
Rhesus Macaque
Macaca mulatta
XP_001104094
376
42450
S281
E
H
L
Y
H
L
E
S
G
L
S
P
P
V
A
Dog
Lupus familis
XP_849816
358
40144
L259
L
Y
H
L
E
S
G
L
S
P
P
V
T
V
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JK81
380
42704
S280
E
H
L
Y
H
L
E
S
E
L
S
P
K
V
A
Rat
Rattus norvegicus
Q641W2
381
42870
S281
E
H
L
Y
H
L
E
S
E
L
S
P
T
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423851
370
41355
K275
E
H
L
F
S
L
E
K
E
L
V
L
P
D
P
Frog
Xenopus laevis
NP_001088807
369
41920
K282
E
H
L
F
Q
L
E
K
E
L
G
L
E
K
Q
Zebra Danio
Brachydanio rerio
NP_001035070
273
31376
Q186
A
L
V
G
S
E
F
Q
D
R
L
L
Y
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623698
329
37728
Q242
L
F
A
I
E
K
E
Q
N
I
K
P
L
L
K
Nematode Worm
Caenorhab. elegans
O17606
340
38446
D253
I
T
Y
I
L
F
S
D
S
T
N
A
S
W
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_199012
373
42281
Q285
L
H
L
F
E
L
E
Q
E
M
K
I
E
P
L
Baker's Yeast
Sacchar. cerevisiae
P40093
338
38156
E251
K
E
H
L
Y
E
L
E
R
E
K
N
I
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96
84
N.A.
85.5
85.8
N.A.
N.A.
56.1
64
43.8
N.A.
N.A.
43.6
41.7
N.A.
Protein Similarity:
100
99.1
97.6
88.3
N.A.
90.7
90.2
N.A.
N.A.
69.4
75
55.5
N.A.
N.A.
61.4
61.4
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
86.6
86.6
N.A.
N.A.
46.6
40
0
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
100
100
100
20
N.A.
86.6
86.6
N.A.
N.A.
53.3
46.6
6.6
N.A.
N.A.
26.6
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
46
40.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63
59.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
8
0
0
0
0
8
0
% D
% Glu:
54
8
0
0
24
16
70
8
39
8
0
0
16
8
0
% E
% Phe:
0
8
0
24
0
8
8
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
0
0
8
0
24
0
8
0
0
0
0
% G
% His:
0
62
16
0
39
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
16
0
0
0
0
0
8
0
8
8
0
0
% I
% Lys:
8
0
0
0
0
8
0
16
0
0
24
0
8
8
16
% K
% Leu:
24
8
62
16
8
62
8
8
0
54
8
24
8
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
0
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
8
8
47
31
8
8
% P
% Gln:
0
0
0
0
8
0
0
24
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
8
% R
% Ser:
0
0
0
0
16
8
8
39
16
0
39
0
8
0
0
% S
% Thr:
0
8
0
0
0
0
0
0
0
8
0
0
16
0
8
% T
% Val:
0
0
8
0
0
0
0
0
0
0
8
8
0
47
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
8
39
8
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _