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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C12orf10 All Species: 5.45
Human Site: S37 Identified Species: 10
UniProt: Q9HB07 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB07 NP_067653 376 42445 S37 S V P P P K R S R S K L M A P
Chimpanzee Pan troglodytes XP_522402 376 42518 S37 S V P P P K R S R S K L M A P
Rhesus Macaque Macaca mulatta XP_001104094 376 42450 P37 S V S P P K R P R S K L M A S
Dog Lupus familis XP_849816 358 40144 E34 D G T F H C D E A L A C A L L
Cat Felis silvestris
Mouse Mus musculus Q9JK81 380 42704 P36 Q D P P A K R P R N N L M A P
Rat Rattus norvegicus Q641W2 381 42870 P37 P D L P P K R P R N N L M A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423851 370 41355 S34 S V G L L Y V S L C P S R L F
Frog Xenopus laevis NP_001088807 369 41920 R39 P E D P K R P R R E E Q A M T
Zebra Danio Brachydanio rerio NP_001035070 273 31376
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_623698 329 37728 D17 H D G C F H C D E A L A C F M
Nematode Worm Caenorhab. elegans O17606 340 38446 Q28 F M L K Q L P Q F K D H S I L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_199012 373 42281 P43 V Y S T A T S P S P S E I S V
Baker's Yeast Sacchar. cerevisiae P40093 338 38156 A26 T H S G S F H A D E S L A V Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96 84 N.A. 85.5 85.8 N.A. N.A. 56.1 64 43.8 N.A. N.A. 43.6 41.7 N.A.
Protein Similarity: 100 99.1 97.6 88.3 N.A. 90.7 90.2 N.A. N.A. 69.4 75 55.5 N.A. N.A. 61.4 61.4 N.A.
P-Site Identity: 100 100 80 0 N.A. 60 60 N.A. N.A. 20 13.3 0 N.A. N.A. 0 0 N.A.
P-Site Similarity: 100 100 80 0 N.A. 66.6 66.6 N.A. N.A. 20 26.6 0 N.A. N.A. 6.6 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 46 40.6 N.A.
Protein Similarity: N.A. N.A. N.A. 63 59.3 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 16 0 0 8 8 8 8 8 24 39 0 % A
% Cys: 0 0 0 8 0 8 8 0 0 8 0 8 8 0 0 % C
% Asp: 8 24 8 0 0 0 8 8 8 0 8 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 8 8 16 8 8 0 0 0 % E
% Phe: 8 0 0 8 8 8 0 0 8 0 0 0 0 8 8 % F
% Gly: 0 8 16 8 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 8 8 0 0 8 8 8 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 0 % I
% Lys: 0 0 0 8 8 39 0 0 0 8 24 0 0 0 0 % K
% Leu: 0 0 16 8 8 8 0 0 8 8 8 47 0 16 16 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 39 8 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 16 16 0 0 0 0 % N
% Pro: 16 0 24 47 31 0 16 31 0 8 8 0 0 0 31 % P
% Gln: 8 0 0 0 8 0 0 8 0 0 0 8 0 0 0 % Q
% Arg: 0 0 0 0 0 8 39 8 47 0 0 0 8 0 0 % R
% Ser: 31 0 24 0 8 0 8 24 8 24 16 8 8 8 8 % S
% Thr: 8 0 8 8 0 8 0 0 0 0 0 0 0 0 8 % T
% Val: 8 31 0 0 0 0 8 0 0 0 0 0 0 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _