Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNK12 All Species: 4.55
Human Site: S13 Identified Species: 9.09
UniProt: Q9HB15 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB15 NP_071338.1 430 46889 S13 P R P P P R R S R R R L P R P
Chimpanzee Pan troglodytes XP_001141129 408 45433 L13 F S W G P G H L N E D N A R F
Rhesus Macaque Macaca mulatta XP_001113593 430 46886 S13 P R P P P R R S R R R L P R P
Dog Lupus familis XP_538483 432 46929 C13 P R P P P R R C R R R L P R P
Cat Felis silvestris
Mouse Mus musculus Q8R1P5 405 44907 L13 C G C S P G H L N E D N A R F
Rat Rattus norvegicus Q9ERS1 430 46946 C13 P R P P P R R C R R R L P R P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506683 300 33479
Chicken Gallus gallus XP_001235376 407 45529 R13 C C C S G A G R L N A D N A R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687561 409 44830 H13 L Q G C R S L H I N E D N G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649891 340 37822
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17185 329 36973
Sea Urchin Strong. purpuratus XP_785246 422 48202 L13 T F C A I L H L K E D N A R F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.8 99.7 97.9 N.A. 59.2 98.8 N.A. 47.9 63.2 N.A. 68.3 N.A. 26.2 N.A. 27.2 46
Protein Similarity: 100 72 100 98.6 N.A. 70.2 99.3 N.A. 57.6 75.3 N.A. 76.9 N.A. 42 N.A. 39.5 60.9
P-Site Identity: 100 13.3 100 93.3 N.A. 13.3 93.3 N.A. 0 0 N.A. 0 N.A. 0 N.A. 0 6.6
P-Site Similarity: 100 13.3 100 93.3 N.A. 13.3 93.3 N.A. 0 0 N.A. 6.6 N.A. 0 N.A. 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 0 9 0 0 0 0 9 0 25 9 0 % A
% Cys: 17 9 25 9 0 0 0 17 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 25 17 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 25 9 0 0 0 0 % E
% Phe: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 25 % F
% Gly: 0 9 9 9 9 17 9 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 0 0 0 25 9 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % K
% Leu: 9 0 0 0 0 9 9 25 9 0 0 34 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 17 17 0 25 17 0 0 % N
% Pro: 34 0 34 34 50 0 0 0 0 0 0 0 34 0 34 % P
% Gln: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 34 0 0 9 34 34 9 34 34 34 0 0 59 17 % R
% Ser: 0 9 0 17 0 9 0 17 0 0 0 0 0 0 0 % S
% Thr: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _