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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK12
All Species:
9.7
Human Site:
S187
Identified Species:
19.39
UniProt:
Q9HB15
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB15
NP_071338.1
430
46889
S187
R
E
R
Q
L
R
R
S
G
L
L
P
A
T
F
Chimpanzee
Pan troglodytes
XP_001141129
408
45433
E174
R
R
G
A
L
P
Q
E
S
L
K
D
A
G
Q
Rhesus Macaque
Macaca mulatta
XP_001113593
430
46886
S187
R
E
R
Q
L
R
R
S
G
L
L
P
A
T
F
Dog
Lupus familis
XP_538483
432
46929
L189
R
Q
L
R
R
S
G
L
L
P
A
S
L
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1P5
405
44907
D174
R
R
G
A
V
T
Q
D
N
M
K
A
P
E
K
Rat
Rattus norvegicus
Q9ERS1
430
46946
S187
R
E
R
Q
L
R
R
S
G
L
L
P
A
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506683
300
33479
G70
L
P
H
D
S
R
R
G
S
G
N
S
E
V
D
Chicken
Gallus gallus
XP_001235376
407
45529
H174
R
R
K
G
V
L
P
H
D
G
R
R
G
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687561
409
44830
P174
R
T
S
G
L
L
P
P
G
I
C
Q
D
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649891
340
37822
F110
V
T
I
P
G
K
A
F
C
M
G
Y
A
M
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
S99
T
T
I
G
Y
G
H
S
T
P
M
T
D
A
G
Sea Urchin
Strong. purpuratus
XP_785246
422
48202
N178
K
I
K
D
Q
H
Q
N
G
Q
A
K
N
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.8
99.7
97.9
N.A.
59.2
98.8
N.A.
47.9
63.2
N.A.
68.3
N.A.
26.2
N.A.
27.2
46
Protein Similarity:
100
72
100
98.6
N.A.
70.2
99.3
N.A.
57.6
75.3
N.A.
76.9
N.A.
42
N.A.
39.5
60.9
P-Site Identity:
100
26.6
100
6.6
N.A.
6.6
100
N.A.
13.3
6.6
N.A.
20
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
33.3
100
20
N.A.
26.6
100
N.A.
13.3
26.6
N.A.
26.6
N.A.
20
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
17
0
0
9
0
0
0
17
9
42
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
0
9
9
0
0
9
17
0
9
% D
% Glu:
0
25
0
0
0
0
0
9
0
0
0
0
9
9
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
0
0
0
9
25
% F
% Gly:
0
0
17
25
9
9
9
9
42
17
9
0
9
17
25
% G
% His:
0
0
9
0
0
9
9
9
0
0
0
0
0
0
0
% H
% Ile:
0
9
17
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
9
0
17
0
0
9
0
0
0
0
17
9
0
0
9
% K
% Leu:
9
0
9
0
42
17
0
9
9
34
25
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
17
9
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
9
9
0
9
0
9
0
0
% N
% Pro:
0
9
0
9
0
9
17
9
0
17
0
25
9
0
0
% P
% Gln:
0
9
0
25
9
0
25
0
0
9
0
9
0
0
9
% Q
% Arg:
67
25
25
9
9
34
34
0
0
0
9
9
0
9
9
% R
% Ser:
0
0
9
0
9
9
0
34
17
0
0
17
0
9
0
% S
% Thr:
9
25
0
0
0
9
0
0
9
0
0
9
0
25
0
% T
% Val:
9
0
0
0
17
0
0
0
0
0
0
0
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _