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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNK12 All Species: 13.33
Human Site: S198 Identified Species: 26.67
UniProt: Q9HB15 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB15 NP_071338.1 430 46889 S198 P A T F R R G S A L S E A D S
Chimpanzee Pan troglodytes XP_001141129 408 45433 D185 D A G Q C E V D S L A G W K P
Rhesus Macaque Macaca mulatta XP_001113593 430 46886 S198 P A T F R R G S A L S E A D S
Dog Lupus familis XP_538483 432 46929 S200 S L R R G S G S A L A E A D G
Cat Felis silvestris
Mouse Mus musculus Q8R1P5 405 44907 D185 A P E K G E A D S L T G W K P
Rat Rattus norvegicus Q9ERS1 430 46946 S198 P A T F R R G S A L S E A D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506683 300 33479 G81 S E V D S L A G W K P S V Y Y
Chicken Gallus gallus XP_001235376 407 45529 A185 R G S G T S E A D S L A G W K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687561 409 44830 L185 Q D F A A S T L P G W K P S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649891 340 37822 L121 Y A M V G I P L G L V M F Q S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17185 329 36973 C110 T D A G K V F C M L Y A L A G
Sea Urchin Strong. purpuratus XP_785246 422 48202 S189 K N G G R R P S E Q S D D D L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.8 99.7 97.9 N.A. 59.2 98.8 N.A. 47.9 63.2 N.A. 68.3 N.A. 26.2 N.A. 27.2 46
Protein Similarity: 100 72 100 98.6 N.A. 70.2 99.3 N.A. 57.6 75.3 N.A. 76.9 N.A. 42 N.A. 39.5 60.9
P-Site Identity: 100 13.3 100 46.6 N.A. 6.6 100 N.A. 0 0 N.A. 0 N.A. 20 N.A. 6.6 33.3
P-Site Similarity: 100 26.6 100 53.3 N.A. 20 100 N.A. 0 13.3 N.A. 6.6 N.A. 20 N.A. 13.3 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 42 9 9 9 0 17 9 34 0 17 17 34 9 0 % A
% Cys: 0 0 0 0 9 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 9 17 0 9 0 0 0 17 9 0 0 9 9 42 0 % D
% Glu: 0 9 9 0 0 17 9 0 9 0 0 34 0 0 0 % E
% Phe: 0 0 9 25 0 0 9 0 0 0 0 0 9 0 0 % F
% Gly: 0 9 17 25 25 0 34 9 9 9 0 17 9 0 17 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 9 9 0 0 0 0 9 0 9 0 17 9 % K
% Leu: 0 9 0 0 0 9 0 17 0 67 9 0 9 0 9 % L
% Met: 0 0 9 0 0 0 0 0 9 0 0 9 0 0 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 25 9 0 0 0 0 17 0 9 0 9 0 9 0 17 % P
% Gln: 9 0 0 9 0 0 0 0 0 9 0 0 0 9 0 % Q
% Arg: 9 0 9 9 34 34 0 0 0 0 0 0 0 0 0 % R
% Ser: 17 0 9 0 9 25 0 42 17 9 34 9 0 9 34 % S
% Thr: 9 0 25 0 9 0 9 0 0 0 9 0 0 0 0 % T
% Val: 0 0 9 9 0 9 9 0 0 0 9 0 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 9 0 17 9 0 % W
% Tyr: 9 0 0 0 0 0 0 0 0 0 9 0 0 9 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _