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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK12
All Species:
10.3
Human Site:
S205
Identified Species:
20.61
UniProt:
Q9HB15
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB15
NP_071338.1
430
46889
S205
S
A
L
S
E
A
D
S
L
A
G
W
K
P
S
Chimpanzee
Pan troglodytes
XP_001141129
408
45433
P192
D
S
L
A
G
W
K
P
S
V
Y
Y
V
M
L
Rhesus Macaque
Macaca mulatta
XP_001113593
430
46886
S205
S
A
L
S
E
A
D
S
L
A
G
W
K
P
S
Dog
Lupus familis
XP_538483
432
46929
G207
S
A
L
A
E
A
D
G
L
A
G
W
K
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1P5
405
44907
P192
D
S
L
T
G
W
K
P
S
V
Y
Y
V
M
L
Rat
Rattus norvegicus
Q9ERS1
430
46946
S205
S
A
L
S
E
A
D
S
L
A
G
W
K
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506683
300
33479
Y88
G
W
K
P
S
V
Y
Y
V
M
L
I
L
C
L
Chicken
Gallus gallus
XP_001235376
407
45529
K192
A
D
S
L
A
G
W
K
P
S
V
Y
Y
V
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687561
409
44830
V192
L
P
G
W
K
P
S
V
Y
H
V
M
L
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649891
340
37822
S128
L
G
L
V
M
F
Q
S
I
G
E
R
L
N
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
G117
C
M
L
Y
A
L
A
G
I
P
L
G
L
I
M
Sea Urchin
Strong. purpuratus
XP_785246
422
48202
L196
S
E
Q
S
D
D
D
L
E
N
W
K
P
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.8
99.7
97.9
N.A.
59.2
98.8
N.A.
47.9
63.2
N.A.
68.3
N.A.
26.2
N.A.
27.2
46
Protein Similarity:
100
72
100
98.6
N.A.
70.2
99.3
N.A.
57.6
75.3
N.A.
76.9
N.A.
42
N.A.
39.5
60.9
P-Site Identity:
100
6.6
100
86.6
N.A.
6.6
100
N.A.
0
0
N.A.
0
N.A.
13.3
N.A.
6.6
20
P-Site Similarity:
100
26.6
100
93.3
N.A.
26.6
100
N.A.
6.6
20
N.A.
6.6
N.A.
20
N.A.
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
34
0
17
17
34
9
0
0
34
0
0
0
0
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
17
9
0
0
9
9
42
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
34
0
0
0
9
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
9
0
17
9
0
17
0
9
34
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
17
0
0
9
0
17
0
% I
% Lys:
0
0
9
0
9
0
17
9
0
0
0
9
34
0
9
% K
% Leu:
17
0
67
9
0
9
0
9
34
0
17
0
34
0
34
% L
% Met:
0
9
0
0
9
0
0
0
0
9
0
9
0
17
17
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% N
% Pro:
0
9
0
9
0
9
0
17
9
9
0
0
9
34
0
% P
% Gln:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
42
17
9
34
9
0
9
34
17
9
0
0
0
9
34
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
9
0
9
9
17
17
0
17
9
9
% V
% Trp:
0
9
0
9
0
17
9
0
0
0
9
34
0
0
0
% W
% Tyr:
0
0
0
9
0
0
9
9
9
0
17
25
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _