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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK12
All Species:
13.64
Human Site:
S339
Identified Species:
27.27
UniProt:
Q9HB15
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB15
NP_071338.1
430
46889
S339
R
N
A
I
T
P
G
S
R
L
R
R
R
L
A
Chimpanzee
Pan troglodytes
XP_001141129
408
45433
V319
N
V
V
M
P
G
S
V
R
N
R
C
N
I
S
Rhesus Macaque
Macaca mulatta
XP_001113593
430
46886
S339
R
N
A
I
T
P
G
S
R
L
R
R
R
L
A
Dog
Lupus familis
XP_538483
432
46929
S341
R
N
A
I
T
P
G
S
R
L
R
R
R
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1P5
405
44907
N318
R
N
V
V
M
P
G
N
I
R
N
R
C
N
I
Rat
Rattus norvegicus
Q9ERS1
430
46946
S339
R
N
A
I
T
P
G
S
R
L
R
R
R
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506683
300
33479
R214
M
P
G
S
I
R
N
R
R
N
I
S
I
E
T
Chicken
Gallus gallus
XP_001235376
407
45529
N319
R
N
V
V
M
P
G
N
V
R
G
R
R
N
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687561
409
44830
R320
I
R
P
G
S
R
L
R
R
G
R
F
G
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649891
340
37822
D254
F
M
T
M
Q
A
E
D
A
K
R
D
E
Q
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
L243
A
A
M
N
L
L
V
L
R
F
L
T
M
N
T
Sea Urchin
Strong. purpuratus
XP_785246
422
48202
H325
R
N
A
I
T
P
G
H
L
Q
R
Q
M
N
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.8
99.7
97.9
N.A.
59.2
98.8
N.A.
47.9
63.2
N.A.
68.3
N.A.
26.2
N.A.
27.2
46
Protein Similarity:
100
72
100
98.6
N.A.
70.2
99.3
N.A.
57.6
75.3
N.A.
76.9
N.A.
42
N.A.
39.5
60.9
P-Site Identity:
100
13.3
100
100
N.A.
33.3
100
N.A.
6.6
40
N.A.
13.3
N.A.
6.6
N.A.
6.6
53.3
P-Site Similarity:
100
33.3
100
100
N.A.
46.6
100
N.A.
6.6
53.3
N.A.
20
N.A.
13.3
N.A.
6.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
42
0
0
9
0
0
9
0
0
0
0
0
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
9
9
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% F
% Gly:
0
0
9
9
0
9
59
0
0
9
9
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
42
9
0
0
0
9
0
9
0
9
9
17
% I
% Lys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% K
% Leu:
0
0
0
0
9
9
9
9
9
34
9
0
0
34
0
% L
% Met:
9
9
9
17
17
0
0
0
0
0
0
0
17
0
0
% M
% Asn:
9
59
0
9
0
0
9
17
0
17
9
0
9
34
0
% N
% Pro:
0
9
9
0
9
59
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
9
0
9
0
17
0
% Q
% Arg:
59
9
0
0
0
17
0
17
67
17
67
50
42
0
0
% R
% Ser:
0
0
0
9
9
0
9
34
0
0
0
9
0
0
17
% S
% Thr:
0
0
9
0
42
0
0
0
0
0
0
9
0
0
25
% T
% Val:
0
9
25
17
0
0
9
9
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _