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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNK12
All Species:
24.24
Human Site:
S357
Identified Species:
48.48
UniProt:
Q9HB15
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB15
NP_071338.1
430
46889
S357
A
D
P
A
A
R
D
S
D
A
E
G
R
R
L
Chimpanzee
Pan troglodytes
XP_001141129
408
45433
S335
E
T
D
G
V
A
E
S
D
T
D
G
R
R
L
Rhesus Macaque
Macaca mulatta
XP_001113593
430
46886
S357
A
D
P
A
A
R
D
S
D
A
E
G
R
R
L
Dog
Lupus familis
XP_538483
432
46929
S359
A
D
P
A
A
R
D
S
D
A
E
G
R
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1P5
405
44907
M333
S
I
E
T
D
G
V
M
E
S
D
T
D
G
R
Rat
Rattus norvegicus
Q9ERS1
430
46946
S357
T
D
P
A
A
R
D
S
D
A
E
G
R
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506683
300
33479
T229
D
G
V
M
E
S
D
T
D
G
R
R
L
S
G
Chicken
Gallus gallus
XP_001235376
407
45529
S336
E
T
D
I
V
N
E
S
D
T
D
G
R
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687561
409
44830
S336
D
S
D
G
P
C
D
S
D
T
E
G
R
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649891
340
37822
A269
A
Q
N
L
A
G
N
A
Q
P
V
T
F
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17185
329
36973
Q258
E
D
E
R
R
D
E
Q
E
A
I
L
A
A
Q
Sea Urchin
Strong. purpuratus
XP_785246
422
48202
S350
V
E
V
T
D
Y
D
S
E
T
D
G
R
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.8
99.7
97.9
N.A.
59.2
98.8
N.A.
47.9
63.2
N.A.
68.3
N.A.
26.2
N.A.
27.2
46
Protein Similarity:
100
72
100
98.6
N.A.
70.2
99.3
N.A.
57.6
75.3
N.A.
76.9
N.A.
42
N.A.
39.5
60.9
P-Site Identity:
100
40
100
100
N.A.
0
93.3
N.A.
13.3
40
N.A.
53.3
N.A.
13.3
N.A.
13.3
33.3
P-Site Similarity:
100
53.3
100
100
N.A.
26.6
93.3
N.A.
20
53.3
N.A.
53.3
N.A.
26.6
N.A.
26.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
34
42
9
0
9
0
42
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
42
25
0
17
9
59
0
67
0
34
0
9
9
9
% D
% Glu:
25
9
17
0
9
0
25
0
25
0
42
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
9
0
17
0
17
0
0
0
9
0
67
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
9
0
0
0
0
0
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
59
% L
% Met:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
9
% M
% Asn:
0
0
9
0
0
9
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
34
0
9
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
9
9
0
0
0
0
0
9
% Q
% Arg:
0
0
0
9
9
34
0
0
0
0
9
9
67
67
9
% R
% Ser:
9
9
0
0
0
9
0
67
0
9
0
0
0
9
0
% S
% Thr:
9
17
0
17
0
0
0
9
0
34
0
17
0
0
0
% T
% Val:
9
0
17
0
17
0
9
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _