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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNK12 All Species: 17.58
Human Site: T336 Identified Species: 35.15
UniProt: Q9HB15 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB15 NP_071338.1 430 46889 T336 L A R R N A I T P G S R L R R
Chimpanzee Pan troglodytes XP_001141129 408 45433 P316 S R R N V V M P G S V R N R C
Rhesus Macaque Macaca mulatta XP_001113593 430 46886 T336 L S R R N A I T P G S R L R R
Dog Lupus familis XP_538483 432 46929 T338 L A R R N A I T P G S R L R R
Cat Felis silvestris
Mouse Mus musculus Q8R1P5 405 44907 M315 R S R R N V V M P G N I R N R
Rat Rattus norvegicus Q9ERS1 430 46946 T336 L S R R N A I T P G S R L R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506683 300 33479 I211 N A V M P G S I R N R R N I S
Chicken Gallus gallus XP_001235376 407 45529 M316 R S R R N V V M P G N V R G R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687561 409 44830 S317 R N A I R P G S R L R R G R F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649891 340 37822 Q251 V L R F M T M Q A E D A K R D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17185 329 36973 L240 V I S A A M N L L V L R F L T
Sea Urchin Strong. purpuratus XP_785246 422 48202 T322 R P R R N A I T P G H L Q R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.8 99.7 97.9 N.A. 59.2 98.8 N.A. 47.9 63.2 N.A. 68.3 N.A. 26.2 N.A. 27.2 46
Protein Similarity: 100 72 100 98.6 N.A. 70.2 99.3 N.A. 57.6 75.3 N.A. 76.9 N.A. 42 N.A. 39.5 60.9
P-Site Identity: 100 20 93.3 100 N.A. 40 93.3 N.A. 13.3 40 N.A. 13.3 N.A. 13.3 N.A. 6.6 60
P-Site Similarity: 100 26.6 100 100 N.A. 60 100 N.A. 13.3 60 N.A. 20 N.A. 26.6 N.A. 13.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 25 9 9 9 42 0 0 9 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 0 0 9 0 9 % F
% Gly: 0 0 0 0 0 9 9 0 9 59 0 0 9 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % H
% Ile: 0 9 0 9 0 0 42 9 0 0 0 9 0 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % K
% Leu: 34 9 0 0 0 0 0 9 9 9 9 9 34 9 0 % L
% Met: 0 0 0 9 9 9 17 17 0 0 0 0 0 0 0 % M
% Asn: 9 9 0 9 59 0 9 0 0 9 17 0 17 9 0 % N
% Pro: 0 9 0 0 9 9 0 9 59 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 0 9 0 9 % Q
% Arg: 34 9 75 59 9 0 0 0 17 0 17 67 17 67 50 % R
% Ser: 9 34 9 0 0 0 9 9 0 9 34 0 0 0 9 % S
% Thr: 0 0 0 0 0 9 0 42 0 0 0 0 0 0 9 % T
% Val: 17 0 9 0 9 25 17 0 0 9 9 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _