Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNK12 All Species: 14.85
Human Site: T75 Identified Species: 29.7
UniProt: Q9HB15 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB15 NP_071338.1 430 46889 T75 A R A R W G A T L R N F S A A
Chimpanzee Pan troglodytes XP_001141129 408 45433 L75 R D E L R G F L R H Y E E A T
Rhesus Macaque Macaca mulatta XP_001113593 430 46886 T75 A R A R W G A T L R N F S A A
Dog Lupus familis XP_538483 432 46929 T75 A R A R W G A T L R N F S A A
Cat Felis silvestris
Mouse Mus musculus Q8R1P5 405 44907 L75 R E E L R G F L R H Y E E A T
Rat Rattus norvegicus Q9ERS1 430 46946 T75 A R A R W G A T L R N F S A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506683 300 33479
Chicken Gallus gallus XP_001235376 407 45529 F75 S R A E L R D F L R E Y E E A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687561 409 44830 F75 S L Q D L S S F L K E Y E A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649891 340 37822 S11 R Q N V R T L S L V V C T F T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O17185 329 36973
Sea Urchin Strong. purpuratus XP_785246 422 48202 E75 N A T F N E T E F M E V L E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 61.8 99.7 97.9 N.A. 59.2 98.8 N.A. 47.9 63.2 N.A. 68.3 N.A. 26.2 N.A. 27.2 46
Protein Similarity: 100 72 100 98.6 N.A. 70.2 99.3 N.A. 57.6 75.3 N.A. 76.9 N.A. 42 N.A. 39.5 60.9
P-Site Identity: 100 13.3 100 100 N.A. 13.3 100 N.A. 0 33.3 N.A. 20 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 13.3 100 100 N.A. 13.3 100 N.A. 0 46.6 N.A. 46.6 N.A. 26.6 N.A. 0 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 9 42 0 0 0 34 0 0 0 0 0 0 59 50 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 0 9 0 9 0 0 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 17 9 0 9 0 9 0 0 25 17 34 17 0 % E
% Phe: 0 0 0 9 0 0 17 17 9 0 0 34 0 9 0 % F
% Gly: 0 0 0 0 0 50 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % K
% Leu: 0 9 0 17 17 0 9 17 59 0 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 9 0 9 0 9 0 0 0 0 0 34 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 25 42 0 34 25 9 0 0 17 42 0 0 0 0 9 % R
% Ser: 17 0 0 0 0 9 9 9 0 0 0 0 34 0 0 % S
% Thr: 0 0 9 0 0 9 9 34 0 0 0 0 9 0 25 % T
% Val: 0 0 0 9 0 0 0 0 0 9 9 9 0 0 0 % V
% Trp: 0 0 0 0 34 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 17 17 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _