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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHA2
All Species:
16.67
Human Site:
T125
Identified Species:
40.74
UniProt:
Q9HB19
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB19
NP_067636.1
425
47255
T125
K
G
G
G
L
P
M
T
T
E
V
L
K
S
L
Chimpanzee
Pan troglodytes
XP_528114
486
53210
T186
K
G
G
G
L
P
M
T
T
E
V
L
K
S
L
Rhesus Macaque
Macaca mulatta
XP_001094841
437
47901
T137
K
G
G
G
L
P
M
T
T
E
V
L
K
S
L
Dog
Lupus familis
XP_539966
425
47240
T125
K
V
G
S
L
P
L
T
T
E
V
I
K
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERS5
425
47361
A125
K
A
G
T
V
P
L
A
T
E
V
L
K
N
L
Rat
Rattus norvegicus
XP_001071937
426
47438
T126
A
G
T
V
P
V
A
T
E
V
L
K
N
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506032
369
41166
K85
A
A
P
L
S
Q
D
K
K
P
Q
R
A
Y
K
Chicken
Gallus gallus
NP_990029
410
45769
T125
K
G
G
A
A
P
P
T
T
E
V
T
K
P
P
Frog
Xenopus laevis
NP_001088876
411
46077
V126
T
P
A
T
A
P
E
V
G
S
A
A
S
G
S
Zebra Danio
Brachydanio rerio
NP_001121835
391
44547
A107
D
L
K
E
W
V
I
A
V
N
N
A
T
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
80.8
86
90.5
N.A.
88.4
86.3
N.A.
61.1
72.9
59.7
51.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
83.1
88.7
94.8
N.A.
92.2
91
N.A.
68.2
81.4
71.2
66.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
60
13.3
N.A.
0
60
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
80
20
N.A.
0
60
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
20
10
10
20
0
10
20
0
0
10
20
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
10
0
10
60
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
60
30
0
0
0
0
10
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% I
% Lys:
60
0
10
0
0
0
0
10
10
0
0
10
60
10
10
% K
% Leu:
0
10
0
10
40
0
20
0
0
0
10
40
0
10
50
% L
% Met:
0
0
0
0
0
0
30
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
10
0
10
10
0
% N
% Pro:
0
10
10
0
10
70
10
0
0
10
0
0
0
10
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
10
10
0
0
0
0
10
0
0
10
40
10
% S
% Thr:
10
0
10
20
0
0
0
60
60
0
0
10
10
0
10
% T
% Val:
0
10
0
10
10
20
0
10
10
10
60
0
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _