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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHA3
All Species:
22.42
Human Site:
T276
Identified Species:
54.81
UniProt:
Q9HB20
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB20
NP_061964.3
300
33861
T276
N
G
D
L
A
S
A
T
I
P
E
E
S
R
L
Chimpanzee
Pan troglodytes
XP_001156880
296
33352
T272
N
G
D
L
A
S
A
T
I
P
E
E
S
R
L
Rhesus Macaque
Macaca mulatta
XP_001099197
300
33788
T276
N
G
D
L
A
S
A
T
I
P
E
E
S
R
L
Dog
Lupus familis
XP_545547
293
32986
T269
N
G
D
L
A
S
A
T
I
P
E
E
S
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERS4
297
33404
S274
T
L
N
G
D
L
A
S
A
T
I
P
E
E
S
Rat
Rattus norvegicus
NP_001013095
299
33542
A276
N
G
D
L
A
S
A
A
I
R
E
E
S
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515413
351
39997
T328
N
G
D
L
T
S
A
T
I
P
E
E
N
R
S
Chicken
Gallus gallus
NP_001026422
300
33879
T276
N
G
D
L
V
S
S
T
I
P
E
E
N
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U3N0
549
61436
L319
Q
E
D
I
Q
T
D
L
E
L
N
E
T
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001197978
511
56706
R412
S
E
I
L
T
G
E
R
D
M
N
L
A
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
98.6
94
N.A.
92
91.6
N.A.
72.9
85.3
N.A.
32.2
N.A.
N.A.
N.A.
N.A.
30.5
Protein Similarity:
100
98.3
99.3
95.6
N.A.
93.3
93.6
N.A.
78
91.3
N.A.
44.2
N.A.
N.A.
N.A.
N.A.
42.8
P-Site Identity:
100
100
100
100
N.A.
6.6
86.6
N.A.
80
73.3
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
86.6
N.A.
86.6
86.6
N.A.
40
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
50
0
70
10
10
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
80
0
10
0
10
0
10
0
0
0
0
0
0
% D
% Glu:
0
20
0
0
0
0
10
0
10
0
70
80
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
70
0
10
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
10
0
0
0
0
70
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
80
0
10
0
10
0
10
0
10
0
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
70
0
10
0
0
0
0
0
0
0
20
0
20
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
60
0
10
0
0
0
% P
% Gln:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
0
0
70
0
% R
% Ser:
10
0
0
0
0
70
10
10
0
0
0
0
50
0
40
% S
% Thr:
10
0
0
0
20
10
0
60
0
10
0
0
10
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _