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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHA1
All Species:
34.55
Human Site:
Y42
Identified Species:
84.44
UniProt:
Q9HB21
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB21
NP_001001974.1
404
45553
Y42
R
E
D
S
F
V
W
Y
M
D
N
P
Q
N
L
Chimpanzee
Pan troglodytes
XP_001159564
404
45505
Y42
R
E
D
S
F
V
W
Y
M
D
N
P
Q
N
L
Rhesus Macaque
Macaca mulatta
XP_001103307
404
45502
Y42
R
E
D
S
F
V
W
Y
M
D
N
P
Q
N
L
Dog
Lupus familis
XP_852584
404
45489
Y42
R
E
D
S
F
V
W
Y
M
D
N
P
Q
N
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BUL6
383
43353
Y42
R
E
D
S
F
V
W
Y
M
D
N
P
Q
N
L
Rat
Rattus norvegicus
NP_001073363
335
38031
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517650
458
51591
Y42
R
E
D
S
L
V
W
Y
M
D
N
P
Q
N
L
Chicken
Gallus gallus
XP_421799
390
44320
Y42
R
E
D
S
L
V
W
Y
M
D
N
P
Q
N
L
Frog
Xenopus laevis
NP_001086540
391
43695
Y42
S
E
N
S
L
L
W
Y
M
D
N
P
Q
N
L
Zebra Danio
Brachydanio rerio
NP_998601
401
44754
Y42
Q
Q
G
S
L
L
W
Y
M
D
N
P
Q
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.2
95
N.A.
76.7
76.2
N.A.
59.8
70.3
64.8
59.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.7
96.7
N.A.
81.1
78.7
N.A.
68.3
77.2
77.7
72
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
93.3
93.3
73.3
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
93.3
93.3
86.6
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
70
0
0
0
0
0
0
90
0
0
0
0
0
% D
% Glu:
0
80
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
40
20
0
0
0
0
0
0
0
0
90
% L
% Met:
0
0
0
0
0
0
0
0
90
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
90
0
0
90
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
90
0
0
0
% P
% Gln:
10
10
0
0
0
0
0
0
0
0
0
0
90
0
0
% Q
% Arg:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
90
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
70
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
90
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _