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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCPEP1 All Species: 33.64
Human Site: S435 Identified Species: 49.33
UniProt: Q9HB40 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB40 NP_067639.1 452 50831 S435 K A G H M V P S D Q G D M A L
Chimpanzee Pan troglodytes XP_001172174 452 50766 S435 K A G H M V P S D Q G N M A L
Rhesus Macaque Macaca mulatta XP_001104815 452 50613 S435 K A G H M V P S D Q G D M A L
Dog Lupus familis XP_537688 477 53125 S460 R A G H M V P S D Q G D M A L
Cat Felis silvestris
Mouse Mus musculus Q920A5 452 50948 S435 K A G H M V P S D Q G E M A L
Rat Rattus norvegicus Q920A6 452 51156 A435 K A G H M V P A D Q G D M A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521733 560 62210 S541 R A G H M V P S D Q G D T A L
Chicken Gallus gallus NP_001012821 446 49959 N421 K A G H M V N N I A I G V P S
Frog Xenopus laevis NP_001088737 443 49367 S424 K A G H M V P S D Q G V T A L
Zebra Danio Brachydanio rerio NP_956486 445 49600 S428 K A G H M I P S D Q G P M A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392686 435 48876 K419 R A G H M V P K D N P A A M G
Nematode Worm Caenorhab. elegans NP_872130 445 50095 Y426 R A G H M V A Y D T P E S A I
Sea Urchin Strong. purpuratus XP_785691 470 52220 A451 K A G H M V P A D A G E A A L
Poplar Tree Populus trichocarpa XP_002313552 489 53783 V450 G A G H F V P V D Q P C I A L
Maize Zea mays NP_001148149 464 50034 L445 E A G H M V P L D N P C P A L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q67Y83 461 51734 V442 G A G H F V P V D E P C V A L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 96 82.8 N.A. 82 82.7 N.A. 60.7 65.9 65.9 62.8 N.A. N.A. 42 41.8 47.8
Protein Similarity: 100 99.3 99.1 88.2 N.A. 90.7 91.8 N.A. 70.7 78.9 77.2 77.6 N.A. N.A. 59.2 58.6 63.6
P-Site Identity: 100 93.3 100 93.3 N.A. 93.3 93.3 N.A. 86.6 40 86.6 86.6 N.A. N.A. 46.6 46.6 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 53.3 86.6 93.3 N.A. N.A. 53.3 66.6 86.6
Percent
Protein Identity: 42.7 45 N.A. 42.9 N.A. N.A.
Protein Similarity: 57.2 58.6 N.A. 60.7 N.A. N.A.
P-Site Identity: 60 60 N.A. 53.3 N.A. N.A.
P-Site Similarity: 66.6 66.6 N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 100 0 0 0 0 7 13 0 13 0 7 13 88 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 94 0 0 32 0 0 0 % D
% Glu: 7 0 0 0 0 0 0 0 0 7 0 19 0 0 0 % E
% Phe: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 13 0 100 0 0 0 0 0 0 0 63 7 0 0 7 % G
% His: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 7 0 7 0 7 0 7 % I
% Lys: 57 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 82 % L
% Met: 0 0 0 0 88 0 0 0 0 0 0 0 44 7 0 % M
% Asn: 0 0 0 0 0 0 7 7 0 13 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 88 0 0 0 32 7 7 7 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 63 0 0 0 0 0 % Q
% Arg: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 50 0 0 0 0 7 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 7 0 0 13 0 0 % T
% Val: 0 0 0 0 0 94 0 13 0 0 0 7 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _