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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SP110 All Species: 6.97
Human Site: T456 Identified Species: 25.56
UniProt: Q9HB58 Number Species: 6
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HB58 NP_004500.3 689 78495 T456 R G K P K S D T V D F H C S K
Chimpanzee Pan troglodytes XP_001140760 689 78494 T456 R G K P K S D T V D F H C S K
Rhesus Macaque Macaca mulatta XP_001111921 753 85946 G506 K C I Q S E D G N W F T P R E
Dog Lupus familis XP_534598 835 95277 H507 P R I P R D T H M D F H R P E
Cat Felis silvestris
Mouse Mus musculus Q8BVK9 445 50122 N257 K K R P N W S N S K R R R Q K
Rat Rattus norvegicus Q3KRF1 478 53186 R290 W S N S K R R R Q K K K P P Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513758 1105 125920 S623 A R Q S Q S Q S V D F R S P Q
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 34.6 23.2 N.A. 34.2 34.9 N.A. 21 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.9 49.4 40.3 N.A. 46.4 47.4 N.A. 34.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 26.6 N.A. 13.3 6.6 N.A. 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 26.6 46.6 N.A. 26.6 13.3 N.A. 53.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 15 0 0 0 0 0 0 0 0 0 0 29 0 0 % C
% Asp: 0 0 0 0 0 15 43 0 0 58 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 29 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 72 0 0 0 0 % F
% Gly: 0 29 0 0 0 0 0 15 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 15 0 0 0 43 0 0 0 % H
% Ile: 0 0 29 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 29 15 29 0 43 0 0 0 0 29 15 15 0 0 43 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % M
% Asn: 0 0 15 0 15 0 0 15 15 0 0 0 0 0 0 % N
% Pro: 15 0 0 58 0 0 0 0 0 0 0 0 29 43 0 % P
% Gln: 0 0 15 15 15 0 15 0 15 0 0 0 0 15 29 % Q
% Arg: 29 29 15 0 15 15 15 15 0 0 15 29 29 15 0 % R
% Ser: 0 15 0 29 15 43 15 15 15 0 0 0 15 29 0 % S
% Thr: 0 0 0 0 0 0 15 29 0 0 0 15 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 43 0 0 0 0 0 0 % V
% Trp: 15 0 0 0 0 15 0 0 0 15 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _