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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACYBP
All Species:
21.21
Human Site:
S48
Identified Species:
35.9
UniProt:
Q9HB71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HB71
NP_001007215.1
228
26210
S48
K
N
K
M
Q
Q
K
S
Q
K
K
A
E
L
L
Chimpanzee
Pan troglodytes
XP_514016
466
51149
S286
K
N
K
M
Q
Q
K
S
Q
K
K
A
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001095373
228
26214
S48
K
N
K
M
Q
Q
K
S
Q
K
K
A
E
L
L
Dog
Lupus familis
XP_537183
230
26417
S50
K
N
K
M
Q
Q
K
S
Q
R
K
A
E
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CXW3
229
26492
S50
K
N
K
M
Q
Q
K
S
Q
K
K
P
E
L
D
Rat
Rattus norvegicus
Q6AYK6
229
26523
S50
R
N
K
M
Q
Q
K
S
Q
K
K
P
E
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515611
229
26307
E50
K
N
K
M
Q
Q
K
E
Q
G
K
R
E
T
A
Chicken
Gallus gallus
XP_422279
221
25575
P46
E
L
E
I
K
N
Q
P
L
P
K
P
K
D
V
Frog
Xenopus laevis
NP_001080214
226
26049
A50
S
T
K
Q
Q
Q
Q
A
G
A
S
M
E
T
Q
Zebra Danio
Brachydanio rerio
NP_998052
227
26166
Q52
A
Q
K
R
Q
Q
K
Q
Q
Q
E
K
K
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572332
230
25765
K46
E
I
V
N
L
E
L
K
A
K
I
A
A
E
R
Honey Bee
Apis mellifera
XP_396161
228
25904
K50
A
R
L
I
E
E
N
K
I
S
H
T
I
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179295
277
30807
G49
K
D
Q
E
E
L
R
G
P
D
E
K
G
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_564346
222
24801
N46
R
D
S
A
V
S
S
N
A
K
P
K
V
P
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.9
96
97.3
N.A.
93
91.6
N.A.
82.5
68.4
70.1
60.5
N.A.
40.8
41.2
N.A.
35.3
Protein Similarity:
100
48.9
98.2
97.8
N.A.
96.5
95.1
N.A.
92.1
83.7
85.5
73.2
N.A.
60.4
65.3
N.A.
55.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
73.3
N.A.
66.6
6.6
26.6
33.3
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
80
N.A.
66.6
53.3
40
53.3
N.A.
26.6
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
8
0
0
0
8
15
8
0
36
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
0
0
0
0
8
0
0
0
15
15
% D
% Glu:
15
0
8
8
15
15
0
8
0
0
15
0
58
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
8
8
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
8
0
15
0
0
0
0
8
0
8
0
8
0
0
% I
% Lys:
50
0
65
0
8
0
58
15
0
50
58
22
15
0
0
% K
% Leu:
0
8
8
0
8
8
8
0
8
0
0
0
0
36
29
% L
% Met:
0
0
0
50
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
50
0
8
0
8
8
8
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
8
8
22
0
8
0
% P
% Gln:
0
8
8
8
65
65
15
8
58
8
0
0
0
0
8
% Q
% Arg:
15
8
0
8
0
0
8
0
0
8
0
8
0
0
8
% R
% Ser:
8
0
8
0
0
8
8
43
0
8
8
0
0
8
15
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
8
0
15
8
% T
% Val:
0
0
8
0
8
0
0
0
0
0
0
0
8
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _