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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RC3H2 All Species: 25.15
Human Site: S670 Identified Species: 55.33
UniProt: Q9HBD1 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBD1 NP_001094058.1 1191 131669 S670 P R D R M N S S P Y Q P P P P
Chimpanzee Pan troglodytes XP_001138799 1191 131678 S670 P R D R M N S S P Y Q P P P P
Rhesus Macaque Macaca mulatta XP_001086139 1191 131708 S670 P R D R M N S S P Y Q P P P P
Dog Lupus familis XP_851569 1189 131620 S670 P R D R M N S S P Y Q P P P P
Cat Felis silvestris
Mouse Mus musculus P0C090 1187 131276 S669 P R D R M N S S P Y Q P P P P
Rat Rattus norvegicus NP_001101309 1187 131402 S669 P R D R M N S S P Y Q P P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512234 1090 120685 Q591 T R L P V Y P Q H S E N I H Y
Chicken Gallus gallus XP_415394 1195 131934 Y671 R D R L N S P Y Q P P P P Q P
Frog Xenopus laevis Q6NUC6 1114 123558 Y611 P Y A Q G V Y Y P P Q S S Q C
Zebra Danio Brachydanio rerio XP_688313 1026 113900 H528 L E Q N L G S H S Q S P S I S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O45962 1014 112294 R516 P Q R F R G G R Q R G A P P P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.5 97.4 N.A. 95.3 95.6 N.A. 83.5 90.5 49 52.3 N.A. N.A. N.A. 24.8 N.A.
Protein Similarity: 100 99.6 99.7 98.6 N.A. 97.2 97.3 N.A. 87.4 94.8 62.3 63.4 N.A. N.A. N.A. 41.9 N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 20 20 13.3 N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 26.6 26.6 20 N.A. N.A. N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 10 55 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 19 10 0 0 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 10 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 10 10 10 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 55 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 10 55 0 0 0 0 0 10 0 0 0 % N
% Pro: 73 0 0 10 0 0 19 0 64 19 10 73 73 64 73 % P
% Gln: 0 10 10 10 0 0 0 10 19 10 64 0 0 19 0 % Q
% Arg: 10 64 19 55 10 0 0 10 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 64 55 10 10 10 10 19 0 10 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 10 10 19 0 55 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _