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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IL21R All Species: 5.15
Human Site: S532 Identified Species: 12.59
UniProt: Q9HBE5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBE5 NP_068570.1 538 59130 S532 V I P P P L S S P G P Q A S _
Chimpanzee Pan troglodytes Q38J84 551 61108 S538 L N T D A Y L S L Q E L Q G Q
Rhesus Macaque Macaca mulatta XP_001094102 490 53595 S484 V I P P P L S S P G P Q A S _
Dog Lupus familis XP_849995 543 58463 G536 V M A P P P E G P G P Q A S E
Cat Felis silvestris
Mouse Mus musculus Q9JHX3 529 58336 D523 V R T P P P V D S G A Q S S _
Rat Rattus norvegicus P26896 537 60639 L523 T L N T D A Y L S L Q E L Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510351 890 98554 R872 C M E N E P P R C Y V K Q W V
Chicken Gallus gallus NP_001025811 590 66314 V572 E D F P R S Y V K Q W I S C H
Frog Xenopus laevis Q4W815 525 59654
Zebra Danio Brachydanio rerio NP_001106982 508 56655 A495 N Y V K Q W V A F T A V Q V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.7 86.9 71.4 N.A. 63.5 22.2 N.A. 29.1 32 20.2 22.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 36.8 89.2 79.1 N.A. 73.2 37.3 N.A. 38.4 47.6 36.6 40.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 6.6 100 60 N.A. 42.8 0 N.A. 0 6.6 0 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 13.3 100 66.6 N.A. 50 13.3 N.A. 13.3 13.3 0 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 10 10 0 10 0 0 20 0 30 0 10 % A
% Cys: 10 0 0 0 0 0 0 0 10 0 0 0 0 10 0 % C
% Asp: 0 10 0 10 10 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 10 0 10 0 10 0 10 0 0 0 10 10 0 0 20 % E
% Phe: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 40 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 20 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 10 0 0 10 0 0 0 % K
% Leu: 10 10 0 0 0 20 10 10 10 10 0 10 10 0 0 % L
% Met: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 10 10 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 20 50 40 30 10 0 30 0 30 0 0 0 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 20 10 40 30 10 10 % Q
% Arg: 0 10 0 0 10 0 0 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 10 20 30 20 0 0 0 20 40 0 % S
% Thr: 10 0 20 10 0 0 0 0 0 10 0 0 0 0 0 % T
% Val: 40 0 10 0 0 0 20 10 0 0 10 10 0 10 10 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 10 0 0 10 0 % W
% Tyr: 0 10 0 0 0 10 20 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 30 % _