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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL21R
All Species:
5.15
Human Site:
Y281
Identified Species:
12.59
UniProt:
Q9HBE5
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBE5
NP_068570.1
538
59130
Y281
E
R
F
F
M
P
L
Y
K
G
C
S
G
D
F
Chimpanzee
Pan troglodytes
Q38J84
551
61108
S293
S
K
F
F
S
Q
L
S
S
E
H
G
G
D
V
Rhesus Macaque
Macaca mulatta
XP_001094102
490
53595
W243
C
S
G
D
F
K
K
W
V
G
A
P
F
T
G
Dog
Lupus familis
XP_849995
543
58463
G284
P
L
Y
V
G
H
S
G
D
F
K
K
W
V
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHX3
529
58336
P279
T
P
E
S
F
F
Q
P
L
Y
R
E
H
S
G
Rat
Rattus norvegicus
P26896
537
60639
L276
C
R
Y
L
G
P
W
L
K
T
L
L
K
C
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510351
890
98554
A591
S
V
K
C
F
S
E
A
F
V
R
H
F
R
R
Chicken
Gallus gallus
NP_001025811
590
66314
Y281
S
A
F
F
K
P
L
Y
L
M
Y
N
G
D
F
Frog
Xenopus laevis
Q4W815
525
59654
M271
G
V
G
V
Y
I
F
M
R
H
G
M
Y
L
K
Zebra Danio
Brachydanio rerio
NP_001106982
508
56655
S253
L
A
L
L
L
V
F
S
G
K
L
G
G
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.7
86.9
71.4
N.A.
63.5
22.2
N.A.
29.1
32
20.2
22.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
36.8
89.2
79.1
N.A.
73.2
37.3
N.A.
38.4
47.6
36.6
40.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
6.6
0
N.A.
0
20
N.A.
0
53.3
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
13.3
6.6
N.A.
0
26.6
N.A.
0
60
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
0
0
10
0
0
10
0
0
0
0
% A
% Cys:
20
0
0
10
0
0
0
0
0
0
10
0
0
10
0
% C
% Asp:
0
0
0
10
0
0
0
0
10
0
0
0
0
30
0
% D
% Glu:
10
0
10
0
0
0
10
0
0
10
0
10
0
0
0
% E
% Phe:
0
0
30
30
30
10
20
0
10
10
0
0
20
0
20
% F
% Gly:
10
0
20
0
20
0
0
10
10
20
10
20
40
0
30
% G
% His:
0
0
0
0
0
10
0
0
0
10
10
10
10
0
10
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
10
10
0
10
10
10
0
20
10
10
10
10
0
20
% K
% Leu:
10
10
10
20
10
0
30
10
20
0
20
10
0
10
0
% L
% Met:
0
0
0
0
10
0
0
10
0
10
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
10
10
0
0
0
30
0
10
0
0
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
20
0
0
0
0
0
0
10
0
20
0
0
10
10
% R
% Ser:
30
10
0
10
10
10
10
20
10
0
0
10
0
10
0
% S
% Thr:
10
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% T
% Val:
0
20
0
20
0
10
0
0
10
10
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
10
10
0
0
0
0
10
0
0
% W
% Tyr:
0
0
20
0
10
0
0
20
0
10
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _