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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE1
All Species:
23.94
Human Site:
S25
Identified Species:
52.67
UniProt:
Q9HBF4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBF4
NP_067083.1
777
87176
S25
C
Q
E
S
Y
A
C
S
G
T
D
E
A
I
F
Chimpanzee
Pan troglodytes
XP_522899
777
87114
S25
C
Q
E
S
Y
A
C
S
G
T
D
E
A
I
F
Rhesus Macaque
Macaca mulatta
XP_001084952
783
86873
P37
R
S
R
S
P
P
P
P
R
K
S
S
L
F
S
Dog
Lupus familis
XP_547890
777
87178
S25
C
Q
E
S
Y
A
C
S
G
T
D
E
A
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q810J8
777
86938
S25
C
Q
E
S
Y
A
C
S
G
T
D
E
A
I
F
Rat
Rattus norvegicus
NP_001100213
777
86886
S25
C
Q
E
S
Y
A
C
S
G
T
D
E
A
V
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520214
286
32088
Chicken
Gallus gallus
XP_421172
781
87690
S25
C
Q
E
S
Y
V
C
S
G
T
D
E
A
V
F
Frog
Xenopus laevis
NP_001086271
783
87540
A25
C
Q
E
K
F
A
C
A
G
N
A
E
A
V
F
Zebra Danio
Brachydanio rerio
XP_001344703
779
86131
G25
C
Q
E
S
Y
A
C
G
G
T
D
E
A
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786799
889
98178
S34
E
S
V
S
S
S
P
S
G
P
K
S
L
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
88.8
96.9
N.A.
96.4
96.2
N.A.
32.1
89.3
79.6
76.8
N.A.
N.A.
N.A.
N.A.
45.8
Protein Similarity:
100
99.8
90.2
98.3
N.A.
97.6
97.8
N.A.
34.6
92.6
86.8
86.1
N.A.
N.A.
N.A.
N.A.
60.6
P-Site Identity:
100
100
6.6
93.3
N.A.
100
93.3
N.A.
0
86.6
60
86.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
0
93.3
80
86.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
64
0
10
0
0
10
0
73
10
0
% A
% Cys:
73
0
0
0
0
0
73
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
64
0
0
0
0
% D
% Glu:
10
0
73
0
0
0
0
0
0
0
0
73
0
10
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
82
% F
% Gly:
0
0
0
0
0
0
0
10
82
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
28
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
10
19
10
0
10
0
0
0
0
0
% P
% Gln:
0
73
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
19
0
82
10
10
0
64
0
0
10
19
0
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
64
0
0
0
0
0
% T
% Val:
0
0
10
0
0
10
0
0
0
0
0
0
0
37
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
64
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _