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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE1
All Species:
34.55
Human Site:
S599
Identified Species:
76
UniProt:
Q9HBF4
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBF4
NP_067083.1
777
87176
S599
P
A
Y
W
R
P
N
S
Q
I
L
S
C
N
K
Chimpanzee
Pan troglodytes
XP_522899
777
87114
S599
P
A
Y
W
R
P
N
S
Q
I
L
S
C
N
K
Rhesus Macaque
Macaca mulatta
XP_001084952
783
86873
S605
P
A
Y
W
R
P
N
S
Q
I
L
S
C
N
K
Dog
Lupus familis
XP_547890
777
87178
S599
P
A
Y
W
R
P
N
S
Q
I
L
S
C
N
K
Cat
Felis silvestris
Mouse
Mus musculus
Q810J8
777
86938
S599
P
A
Y
W
R
P
N
S
Q
I
L
S
C
N
Q
Rat
Rattus norvegicus
NP_001100213
777
86886
S599
P
A
Y
W
R
P
N
S
Q
I
L
S
C
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520214
286
32088
V132
V
L
A
I
S
D
L
V
I
Y
R
T
H
A
D
Chicken
Gallus gallus
XP_421172
781
87690
S603
P
A
Y
W
R
P
N
S
Q
I
L
S
C
N
K
Frog
Xenopus laevis
NP_001086271
783
87540
S604
P
G
Y
W
K
P
N
S
Q
I
L
E
C
T
K
Zebra Danio
Brachydanio rerio
XP_001344703
779
86131
S600
P
A
Y
W
K
P
N
S
L
I
L
R
C
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786799
889
98178
A710
P
P
Y
W
R
P
N
A
E
I
T
A
C
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
88.8
96.9
N.A.
96.4
96.2
N.A.
32.1
89.3
79.6
76.8
N.A.
N.A.
N.A.
N.A.
45.8
Protein Similarity:
100
99.8
90.2
98.3
N.A.
97.6
97.8
N.A.
34.6
92.6
86.8
86.1
N.A.
N.A.
N.A.
N.A.
60.6
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
0
100
73.3
73.3
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
6.6
100
80
80
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
73
10
0
0
0
0
10
0
0
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
91
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
10
91
0
0
0
0
0
% I
% Lys:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
64
% K
% Leu:
0
10
0
0
0
0
10
0
10
0
82
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
91
0
0
0
0
0
0
64
0
% N
% Pro:
91
10
0
0
0
91
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
73
0
0
0
0
0
28
% Q
% Arg:
0
0
0
0
73
0
0
0
0
0
10
10
0
0
0
% R
% Ser:
0
0
0
0
10
0
0
82
0
0
0
64
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
0
% T
% Val:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
91
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
91
0
0
0
0
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _