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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE1
All Species:
35.45
Human Site:
T533
Identified Species:
78
UniProt:
Q9HBF4
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBF4
NP_067083.1
777
87176
T533
G
N
Q
D
P
V
D
T
V
V
R
T
E
I
V
Chimpanzee
Pan troglodytes
XP_522899
777
87114
T533
G
N
Q
D
P
V
D
T
V
V
R
T
E
I
V
Rhesus Macaque
Macaca mulatta
XP_001084952
783
86873
T539
G
N
Q
D
P
V
D
T
V
V
R
T
E
I
V
Dog
Lupus familis
XP_547890
777
87178
T533
G
N
Q
D
P
V
D
T
V
V
R
T
E
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q810J8
777
86938
T533
G
N
Q
D
P
V
D
T
V
V
R
T
E
I
V
Rat
Rattus norvegicus
NP_001100213
777
86886
T533
G
N
Q
D
P
V
D
T
V
V
R
T
E
I
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520214
286
32088
E75
H
T
F
F
Y
G
R
E
V
F
K
T
S
P
A
Chicken
Gallus gallus
XP_421172
781
87690
T537
G
N
Q
D
P
V
N
T
V
V
R
T
E
I
E
Frog
Xenopus laevis
NP_001086271
783
87540
T538
G
N
Q
D
P
V
D
T
V
V
R
T
E
I
Q
Zebra Danio
Brachydanio rerio
XP_001344703
779
86131
T534
G
N
Q
D
P
V
D
T
V
V
R
T
E
I
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786799
889
98178
D644
G
N
Q
E
P
E
M
D
A
V
R
T
E
I
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
88.8
96.9
N.A.
96.4
96.2
N.A.
32.1
89.3
79.6
76.8
N.A.
N.A.
N.A.
N.A.
45.8
Protein Similarity:
100
99.8
90.2
98.3
N.A.
97.6
97.8
N.A.
34.6
92.6
86.8
86.1
N.A.
N.A.
N.A.
N.A.
60.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
86.6
93.3
93.3
N.A.
N.A.
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
93.3
93.3
93.3
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
82
0
0
73
10
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
10
0
10
0
0
0
0
91
0
10
% E
% Phe:
0
0
10
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
91
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
91
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
91
0
0
0
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
91
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
91
0
0
0
0
0
0
0
0
0
0
0
19
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
91
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
0
10
0
0
0
0
0
82
0
0
0
100
0
0
0
% T
% Val:
0
0
0
0
0
82
0
0
91
91
0
0
0
0
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _