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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V0A4 All Species: 31.21
Human Site: S346 Identified Species: 62.42
UniProt: Q9HBG4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBG4 NP_065683.2 840 96358 S346 L E Q G M E L S G S S M A P I
Chimpanzee Pan troglodytes XP_511508 838 96562 S351 L R R G T E H S G S T V P S I
Rhesus Macaque Macaca mulatta XP_001105743 987 112668 S495 L E Q G M E L S G S S M A P I
Dog Lupus familis XP_539895 839 96055 S346 L E Q G M E L S G S S M V P I
Cat Felis silvestris
Mouse Mus musculus Q920R6 833 95587 S346 L E Q G M E L S G S S M I P I
Rat Rattus norvegicus P25286 838 96309 S344 L R R G T E H S G S T V P S I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9I8D0 838 95966 S344 L R R G T E H S G S T V P S I
Frog Xenopus laevis Q8AVM5 831 95538 S344 L R R G T E H S G S T V P S I
Zebra Danio Brachydanio rerio NP_001018502 839 95617 S344 L R R G T E R S G S T V P S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30628 905 103383 S380 L K R G T D E S G S Q V P S I
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32563 840 95510 L360 L G E M I A R L G I D V P S I
Red Bread Mold Neurospora crassa Q01290 856 97974 A365 L Q D V N N R A G L S V P S I
Conservation
Percent
Protein Identity: 100 61.9 83.5 90.9 N.A. 85.8 62.2 N.A. N.A. 61.3 61.4 60.5 N.A. N.A. N.A. 51.1 N.A.
Protein Similarity: 100 77.3 84.3 95.4 N.A. 91.9 76.9 N.A. N.A. 76.6 77 76.3 N.A. N.A. N.A. 66.9 N.A.
P-Site Identity: 100 46.6 100 93.3 N.A. 93.3 46.6 N.A. N.A. 46.6 46.6 46.6 N.A. N.A. N.A. 40 N.A.
P-Site Similarity: 100 66.6 100 93.3 N.A. 93.3 66.6 N.A. N.A. 66.6 66.6 66.6 N.A. N.A. N.A. 66.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 39.5 41.2
Protein Similarity: N.A. N.A. N.A. N.A. 59.4 60.9
P-Site Identity: N.A. N.A. N.A. N.A. 20 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 40 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 9 0 0 0 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 9 0 0 0 0 9 0 0 0 0 % D
% Glu: 0 34 9 0 0 75 9 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 84 0 0 0 0 100 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 34 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 9 0 0 9 0 100 % I
% Lys: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 100 0 0 0 0 0 34 9 0 9 0 0 0 0 0 % L
% Met: 0 0 0 9 34 0 0 0 0 0 0 34 0 0 0 % M
% Asn: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 67 34 0 % P
% Gln: 0 9 34 0 0 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 42 50 0 0 0 25 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 84 0 84 42 0 0 67 0 % S
% Thr: 0 0 0 0 50 0 0 0 0 0 42 0 0 0 0 % T
% Val: 0 0 0 9 0 0 0 0 0 0 0 67 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _