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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP6V0A4
All Species:
13.94
Human Site:
S500
Identified Species:
27.88
UniProt:
Q9HBG4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HBG4
NP_065683.2
840
96358
S500
N
T
H
V
M
E
E
S
L
Y
L
Q
L
D
P
Chimpanzee
Pan troglodytes
XP_511508
838
96562
G503
W
T
E
E
T
L
R
G
N
P
V
L
Q
L
N
Rhesus Macaque
Macaca mulatta
XP_001105743
987
112668
N649
N
T
H
V
M
E
E
N
P
Y
L
Q
L
D
P
Dog
Lupus familis
XP_539895
839
96055
N500
N
T
Y
V
M
E
T
N
P
Y
L
Q
L
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q920R6
833
95587
S500
N
T
H
I
V
E
N
S
P
Y
L
Q
L
D
P
Rat
Rattus norvegicus
P25286
838
96309
S498
T
E
E
T
L
L
G
S
S
V
L
Q
L
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9I8D0
838
95966
T498
S
D
E
L
L
K
T
T
P
L
L
Q
L
D
P
Frog
Xenopus laevis
Q8AVM5
831
95538
S498
E
D
L
L
K
H
T
S
V
L
Q
L
N
P
N
Zebra Danio
Brachydanio rerio
NP_001018502
839
95617
S498
W
T
D
Q
T
L
E
S
N
S
V
L
Q
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P30628
905
103383
S534
Y
L
D
D
E
K
R
S
E
S
Q
L
I
L
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32563
840
95510
T513
I
T
A
T
S
V
G
T
Y
P
I
G
L
D
W
Red Bread Mold
Neurospora crassa
Q01290
856
97974
R517
M
T
V
K
A
V
L
R
E
P
N
G
Y
R
Y
Conservation
Percent
Protein Identity:
100
61.9
83.5
90.9
N.A.
85.8
62.2
N.A.
N.A.
61.3
61.4
60.5
N.A.
N.A.
N.A.
51.1
N.A.
Protein Similarity:
100
77.3
84.3
95.4
N.A.
91.9
76.9
N.A.
N.A.
76.6
77
76.3
N.A.
N.A.
N.A.
66.9
N.A.
P-Site Identity:
100
6.6
86.6
73.3
N.A.
73.3
33.3
N.A.
N.A.
33.3
6.6
20
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
93.3
86.6
N.A.
86.6
46.6
N.A.
N.A.
66.6
20
26.6
N.A.
N.A.
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
39.5
41.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
59.4
60.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
17
9
0
0
0
0
0
0
0
0
0
50
0
% D
% Glu:
9
9
25
9
9
34
25
0
17
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
17
9
0
0
0
17
0
0
0
% G
% His:
0
0
25
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
9
0
0
0
0
0
0
9
0
9
0
0
% I
% Lys:
0
0
0
9
9
17
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
9
17
17
25
9
0
9
17
50
34
59
25
0
% L
% Met:
9
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
34
0
0
0
0
0
9
17
17
0
9
0
9
9
25
% N
% Pro:
0
0
0
0
0
0
0
0
34
25
0
0
0
9
59
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
17
50
17
0
0
% Q
% Arg:
0
0
0
0
0
0
17
9
0
0
0
0
0
9
0
% R
% Ser:
9
0
0
0
9
0
0
50
9
17
0
0
0
0
0
% S
% Thr:
9
67
0
17
17
0
25
17
0
0
0
0
0
0
0
% T
% Val:
0
0
9
25
9
17
0
0
9
9
17
0
0
0
0
% V
% Trp:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% W
% Tyr:
9
0
9
0
0
0
0
0
9
34
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _