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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V0A4 All Species: 9.09
Human Site: S689 Identified Species: 18.18
UniProt: Q9HBG4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.55
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBG4 NP_065683.2 840 96358 S689 E N I E G D S S S P S S R S G
Chimpanzee Pan troglodytes XP_511508 838 96562 E692 V G N G P T E E D A E I I Q H
Rhesus Macaque Macaca mulatta XP_001105743 987 112668 S838 E N I E G D S S S P S S G S G
Dog Lupus familis XP_539895 839 96055 S689 D V E G D N S S P S G S T G Q
Cat Felis silvestris
Mouse Mus musculus Q920R6 833 95587 S689 E G D H S G H S S K K T A G A
Rat Rattus norvegicus P25286 838 96309 E686 V G N G P T E E D A E I I Q H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9I8D0 838 95966 E686 V G N G P T E E D A E I I Q H
Frog Xenopus laevis Q8AVM5 831 95538 E685 V G N G P T E E D A E I I Q H
Zebra Danio Brachydanio rerio NP_001018502 839 95617 D687 V G N G P T E D E A E I I D H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30628 905 103383 T733 Q S R Y S T L T A E S N Q H Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32563 840 95510 E695 A M D A D D A E E E E V G S G
Red Bread Mold Neurospora crassa Q01290 856 97974 N702 D D E E D P S N G D D Y E G A
Conservation
Percent
Protein Identity: 100 61.9 83.5 90.9 N.A. 85.8 62.2 N.A. N.A. 61.3 61.4 60.5 N.A. N.A. N.A. 51.1 N.A.
Protein Similarity: 100 77.3 84.3 95.4 N.A. 91.9 76.9 N.A. N.A. 76.6 77 76.3 N.A. N.A. N.A. 66.9 N.A.
P-Site Identity: 100 0 93.3 20 N.A. 20 0 N.A. N.A. 0 0 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 0 93.3 33.3 N.A. 26.6 0 N.A. N.A. 0 0 0 N.A. N.A. N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 39.5 41.2
Protein Similarity: N.A. N.A. N.A. N.A. 59.4 60.9
P-Site Identity: N.A. N.A. N.A. N.A. 20 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 9 0 0 9 0 9 42 0 0 9 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 17 9 17 0 25 25 0 9 34 9 9 0 0 9 0 % D
% Glu: 25 0 17 25 0 0 42 42 17 17 50 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 50 0 50 17 9 0 0 9 0 9 0 17 25 25 % G
% His: 0 0 0 9 0 0 9 0 0 0 0 0 0 9 42 % H
% Ile: 0 0 17 0 0 0 0 0 0 0 0 42 42 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 9 9 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 17 42 0 0 9 0 9 0 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 42 9 0 0 9 17 0 0 0 0 0 % P
% Gln: 9 0 0 0 0 0 0 0 0 0 0 0 9 34 17 % Q
% Arg: 0 0 9 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 9 0 0 17 0 34 34 25 9 25 25 0 25 0 % S
% Thr: 0 0 0 0 0 50 0 9 0 0 0 9 9 0 0 % T
% Val: 42 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _