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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP6V0A4 All Species: 26.06
Human Site: T125 Identified Species: 52.12
UniProt: Q9HBG4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9HBG4 NP_065683.2 840 96358 T125 K Q S F L E L T E L K Y L L K
Chimpanzee Pan troglodytes XP_511508 838 96562 T126 K R N F L E L T E L K F I L R
Rhesus Macaque Macaca mulatta XP_001105743 987 112668 T274 K K S F L E L T E L K Y L L K
Dog Lupus familis XP_539895 839 96055 T125 K K S F L E L T E L K H L L K
Cat Felis silvestris
Mouse Mus musculus Q920R6 833 95587 T125 K K S F L E L T E L K Y L L K
Rat Rattus norvegicus P25286 838 96309 L123 E A L K R N F L E L T E L K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9I8D0 838 95966 L123 E A L K R N F L E L T E L K F
Frog Xenopus laevis Q8AVM5 831 95538 L123 E A L K R N F L E L T E L K F
Zebra Danio Brachydanio rerio NP_001018502 839 95617 L123 E A L K K N F L E L T E L K H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P30628 905 103383 T138 K K N F S E L T E L K H I L R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32563 840 95510 E139 E V Q K N D L E Q Y R F I L Q
Red Bread Mold Neurospora crassa Q01290 856 97974 T133 K K R E V E L T E W R W V L R
Conservation
Percent
Protein Identity: 100 61.9 83.5 90.9 N.A. 85.8 62.2 N.A. N.A. 61.3 61.4 60.5 N.A. N.A. N.A. 51.1 N.A.
Protein Similarity: 100 77.3 84.3 95.4 N.A. 91.9 76.9 N.A. N.A. 76.6 77 76.3 N.A. N.A. N.A. 66.9 N.A.
P-Site Identity: 100 66.6 93.3 86.6 N.A. 93.3 20 N.A. N.A. 20 20 20 N.A. N.A. N.A. 60 N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 26.6 N.A. N.A. 26.6 26.6 26.6 N.A. N.A. N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 39.5 41.2
Protein Similarity: N.A. N.A. N.A. N.A. 59.4 60.9
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 40
P-Site Similarity: N.A. N.A. N.A. N.A. 60 80
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 34 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 42 0 0 9 0 59 0 9 92 0 0 34 0 0 0 % E
% Phe: 0 0 0 50 0 0 34 0 0 0 0 17 0 0 25 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 9 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % I
% Lys: 59 42 0 42 9 0 0 0 0 0 50 0 0 34 34 % K
% Leu: 0 0 34 0 42 0 67 34 0 84 0 0 67 67 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 17 0 9 34 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 9 9 0 0 0 0 0 9 0 0 0 0 0 9 % Q
% Arg: 0 9 9 0 25 0 0 0 0 0 17 0 0 0 25 % R
% Ser: 0 0 34 0 9 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 59 0 0 34 0 0 0 0 % T
% Val: 0 9 0 0 9 0 0 0 0 0 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 25 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _